The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases
[EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promote...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2014 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/158882 |
| Acceso en línea: | http://hdl.handle.net/10366/158882 |
| Access Level: | acceso abierto |
| Palabra clave: | Asthma Atopy Prostaglandin D(2) Prostaglandin D(2) receptor Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética |
| Sumario: | [EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promoter region, in the differential binding of transcription factors, and thus in PTGDR expression, which appear to be associated to the development of asthma or of susceptibility to the disease. |
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