Palladium-Catalyzed Transformations of Alkylidenecyclopropanes

Organic synthesis has profoundly impacted fields such as medicinal chemistry, materials science, and agriculture by enabling the creation of complex molecular structures beyond those found in nature. In recent years, the field has embraced sustainable practices aligned with green chemistry principle...

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Detalhes bibliográficos
Autor: Rodiño Balboa, Ricardo
Tipo de documento: tese
Data de publicação:2025
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositório:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglês
OAI Identifier:oai:minerva.usc.gal:10347/41048
Acesso em linha:https://hdl.handle.net/10347/41048
Access Level:Acceso aberto
Palavra-chave:alkylidenecyclopropane
palladium
transition-metal catalysis
heterocycles
cross-coupling
230610 Compuestos heterocíclicos
230611 Compuestos organometálicos
230615 Mecanismos de reacción
Descrição
Resumo:Organic synthesis has profoundly impacted fields such as medicinal chemistry, materials science, and agriculture by enabling the creation of complex molecular structures beyond those found in nature. In recent years, the field has embraced sustainable practices aligned with green chemistry principles, prioritizing efficiency, environmental responsibility, and atom economy. In this context, catalysis has emerged as a key synthetic tool, driving more selective and efficient reactions, often under milder conditions, and thereby reducing waste and energy consumption. Among homogeneous catalytic methods, where catalysts and reactants are in the same phase, organometallic complexes featuring transition metals stand out for their tunable electronic and steric properties, which have afforded to broaden significantly the range of achievable chemical transformations, making previously challenging reactions feasible.