From conventional to dual Co/photoredox mediated reductive coupling of alkynes and alkenes

Metal-catalyzed reductive coupling reactions between alkenes and alkynes are a long-standing tradition as a way to create complex unsaturated building blocks of value in organic synthesis ventures. Here, we review the general synthetic approaches realized under Co-catalysis utilizing chemical reduct...

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Detalles Bibliográficos
Autores: Tóth, Balázs L., Amos, Stephanie G. E., Kleij, Arjan W.
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/480089
Acceso en línea:http://hdl.handle.net/2072/480089
https://doi.org/10.1039/D4QO02143F
Access Level:acceso abierto
Palabra clave:Química
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Descripción
Sumario:Metal-catalyzed reductive coupling reactions between alkenes and alkynes are a long-standing tradition as a way to create complex unsaturated building blocks of value in organic synthesis ventures. Here, we review the general synthetic approaches realized under Co-catalysis utilizing chemical reductants, albeit with some limitations in scope and user-friendliness. A more recent advancement shows that these reductive ene–yne coupling reactions can also be accommodated by photoredox catalysis marking a stepping stone in the area, and creating new incentives for this kind of carbon–carbon bond formation and beyond.