Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent

We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection...

Descripción completa

Detalles Bibliográficos
Autores: Molina, Ricardo, Ghosh, Debashis, Carrillo, Eugenia, Monnerat, Séverine, Bern, Caryn, Mondal, Dinesh, Alvar, Jorge
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/13961
Acceso en línea:http://hdl.handle.net/20.500.12105/13961
Access Level:acceso abierto
Palabra clave:Leishmania donovani
Leishmaniasis, Visceral
Adult
Animals
DNA, Protozoan
Female
Humans
India
Male
Polymerase Chain Reaction
Psychodidae
Skin
Xenodiagnosis
Young Adult
id ES_5fa1d0aa3a37fa9ccb1f3e41d94fb369
oai_identifier_str oai:repisalud.isciii.es:20.500.12105/13961
network_acronym_str ES
network_name_str España
repository_id_str
spelling Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian SubcontinentMolina, RicardoGhosh, DebashisCarrillo, EugeniaMonnerat, SéverineBern, CarynMondal, DineshAlvar, JorgeLeishmania donovaniLeishmaniasis, VisceralAdultAnimalsDNA, ProtozoanFemaleHumansIndiaMalePolymerase Chain ReactionPsychodidaeSkinXenodiagnosisYoung AdultWe compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.Oxford University PressWorld Health Organization (WHO/OMS)Fundación CSAI (Salud, Infancia y Bienestar Social)International Centre for Diarrhoeal Disease Research, Bangladesh (India)20222022-04-0720172017-07-0120172017-07-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12105/13961reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/139612026-06-12T12:43:37Z
dc.title.none.fl_str_mv Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
title Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
spellingShingle Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
Molina, Ricardo
Leishmania donovani
Leishmaniasis, Visceral
Adult
Animals
DNA, Protozoan
Female
Humans
India
Male
Polymerase Chain Reaction
Psychodidae
Skin
Xenodiagnosis
Young Adult
title_short Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
title_full Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
title_fullStr Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
title_full_unstemmed Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
title_sort Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent
dc.creator.none.fl_str_mv Molina, Ricardo
Ghosh, Debashis
Carrillo, Eugenia
Monnerat, Séverine
Bern, Caryn
Mondal, Dinesh
Alvar, Jorge
author Molina, Ricardo
author_facet Molina, Ricardo
Ghosh, Debashis
Carrillo, Eugenia
Monnerat, Séverine
Bern, Caryn
Mondal, Dinesh
Alvar, Jorge
author_role author
author2 Ghosh, Debashis
Carrillo, Eugenia
Monnerat, Séverine
Bern, Caryn
Mondal, Dinesh
Alvar, Jorge
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv World Health Organization (WHO/OMS)
Fundación CSAI (Salud, Infancia y Bienestar Social)
International Centre for Diarrhoeal Disease Research, Bangladesh (India)
dc.subject.none.fl_str_mv Leishmania donovani
Leishmaniasis, Visceral
Adult
Animals
DNA, Protozoan
Female
Humans
India
Male
Polymerase Chain Reaction
Psychodidae
Skin
Xenodiagnosis
Young Adult
topic Leishmania donovani
Leishmaniasis, Visceral
Adult
Animals
DNA, Protozoan
Female
Humans
India
Male
Polymerase Chain Reaction
Psychodidae
Skin
Xenodiagnosis
Young Adult
description We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-07-01
2017
2017-07-01
2022
2022-04-07
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/13961
url http://hdl.handle.net/20.500.12105/13961
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869409221525635072
score 15,81155

Similares en LA Referencia