The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis
[Background:] Colorectal cancer (CRC) is a common malignant tumor of the digestive tract. Screening of high risk populations and early diagnosis of CRC are of great importance. Tissue factor pathway inhibitor 2 (TFPI2) methylation is an important indicator for screening CRC. However, the sensitivity...
| Autores: | , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/400628 |
| Acceso en línea: | http://hdl.handle.net/10261/400628 https://api.elsevier.com/content/abstract/scopus_id/105009641598 |
| Access Level: | acceso abierto |
| Palabra clave: | Colorectal cancer (CRC) Meta-analysis Methylation Tissue factor pathway inhibitor 2 (TFPI2) |
| Sumario: | [Background:] Colorectal cancer (CRC) is a common malignant tumor of the digestive tract. Screening of high risk populations and early diagnosis of CRC are of great importance. Tissue factor pathway inhibitor 2 (TFPI2) methylation is an important indicator for screening CRC. However, the sensitivity and specificity of TFPI2 methylation vary significantly across different studies, and its diagnostic performance is susceptible to the influence of detection methods and sample types. This study set out to evaluate the diagnostic value of TFPI2 methylation in blood and stool samples for CRC. |
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