Studies on the Interaction of Isocyanides with Imines: Reaction Scope and Mechanistic Variations

The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon-nitrogen double bond of the imine to form the 4-membered ring system. The scope of the reaction...

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Bibliographic Details
Authors: Ghashghaei, Ouldouz, Manna, Consiglia Annamaria, Vicente García, Esther, Revés, Marc, Lavilla Grífols, Rodolfo
Format: article
Status:Published version
Publication Date:2014
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/120563
Online Access:https://hdl.handle.net/2445/120563
Access Level:Open access
Keyword:Isonitrils
Imines
Compostos heterocíclics
Reaccions químiques
Química orgànica
Isocyanides
Heterocyclic compounds
Chemical reactions
Organic chemistry
Description
Summary:The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon-nitrogen double bond of the imine to form the 4-membered ring system. The scope of the reaction regarding the imine and isocyanide ranges has been determined, and also some mechanistic variations and structural features have been described.