Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

[Background]: In this study, we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in goats. To achieve these two goals, we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granad...

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Detalles Bibliográficos
Autores: Guan, Dailu, Landi, Vincenzo, Luigi-Sierra, Maria Gracia, Delgado, Juan Vicente, Such, Xavier, Castelló, Anna, Cabrera, Betlem, Mármol-Sánchez, Emilio, Fernández-Álvarez, Javier, Ruiz de la Torre, José Luis, Martínez, Amparo, Jordana, Jordi, Amills, Marcel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/228975
Acceso en línea:http://hdl.handle.net/10261/228975
Access Level:acceso abierto
Descripción
Sumario:[Background]: In this study, we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in goats. To achieve these two goals, we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points, i.e. 78 d (T1, early lactation), 216 d (T2, late lactation) and 285 d (T3, dry period) after parturition. Moreover, we have performed a genome-wide association study (GWAS) for seven dairy traits recorded in the 1st lactation of 822 Murciano-Granadina goats.