Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

Background:In this study, we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in goats. To achieve these two goals, we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina...

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Detalles Bibliográficos
Autores: Guan, Dailu|||0000-0001-8800-3158, Landi, Vincenzo|||0000-0003-1385-8439, Luigi Sierra, Maria Gracia|||0000-0002-6414-0550, Delgado Bermejo, Juan Vicente|||0000-0003-1657-8838, Such i Martí, Francesc Xavier|||0000-0002-9712-4477, Castelló Farré, Anna|||0000-0001-8497-6251, Cabrera Pane, Betlem|||0000-0003-2702-5374, Mármol-Sánchez, Emilio|||0000-0002-4393-1740, Fernández Álvarez, Javier|||0000-0003-0450-5869, De La Torre Casañas, José Luis, Martinez, Amparo|||0000-0002-6944-0501, Jordana i Vidal, Jordi|||0000-0002-7789-2989, Amills i Eras, Marcel|||0000-0002-8999-0770
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:236998
Acceso en línea:https://ddd.uab.cat/record/236998
https://dx.doi.org/urn:doi:10.1186/s40104-020-00435-4
Access Level:acceso abierto
Palabra clave:Casein genes
Dairy traits
GWAS
Lactation
QTLs
RNA-Seq
Descripción
Sumario:Background:In this study, we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in goats. To achieve these two goals, we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points, i.e. 78 d (T1, early lactation), 216 d (T2, late lactation) and 285 d (T3, dry period) after parturition. Moreover, we have performed a genome-wide association study (GWAS) for seven dairy traits recorded in the 1st lactation of 822 Murciano-Granadina goats.

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