Occurrence of melatonin and indolic compounds derived from L-tryptophan yeast metabolism in fermented wort and commercial beers

Melatonin and serotonin are bioactive compounds present in foods and beverages and related to neuroprotection and anti-angiogenesis, among other activities. They have been described in wines and the role of yeast in their formation is clear. Thus, this study evaluates the content of these bioactives...

Descripción completa

Detalles Bibliográficos
Autores: Fernández Cruz, Edwin, Carrasco Galán, Fernando, Cerezo López, Ana Belén, Valero, Eva, Morcillo Parra, M. Ángeles, Beltran, Gemma, Torija, María Jesús, Troncoso González, Ana María, García Parrilla, María del Carmen
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/151380
Acceso en línea:https://hdl.handle.net/11441/151380
https://doi.org/10.1016/j.foodchem.2020.127192
Access Level:acceso abierto
Palabra clave:3-Indoleacetic acid
Beer
Bioactive
Fermentation
HRMS
Melatonin
Saccharomyces cerevisiae
Descripción
Sumario:Melatonin and serotonin are bioactive compounds present in foods and beverages and related to neuroprotection and anti-angiogenesis, among other activities. They have been described in wines and the role of yeast in their formation is clear. Thus, this study evaluates the content of these bioactives and other related indolic compounds in beer. For this purpose, commercial beers were analyzed by a validated UHPLC-HRMS method and sample treatment optimized due to the low concentrations expected. Moreover, a wort was fermented with different commercial beer yeast (Abbaye, Diamond, SafAle, SafLager) in order to monitor the formation of these bioactives during the elaboration process. Results show that indolic compounds such as N-acetylserotonin and 3-indoleacetic acid are produced during the alcoholic fermentation of wort. Moreover, the occurrence of four indolic compounds (5-hydroxytryptophan, N-acetylserotonin, 3-indoleacetic acid, L-tryptophan ethyl ester) in commercial beers is reported for the first time.