Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors

Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions....

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Detalles Bibliográficos
Autores: Pérez-Lorente, Alicia Isabel, Araujo-Garrido, Mario, de Vicente, Antonio, Romero, Diego, Molina-Santiago, Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/388155
Acceso en línea:http://hdl.handle.net/10261/388155
https://api.elsevier.com/content/abstract/scopus_id/105001734033
Access Level:acceso abierto
Palabra clave:Pseudomonas putida
Antibacterial activity
Antifungal activity
Effectors
Genetic engineering
T6SS
Descripción
Sumario:Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions. In recent years, T6SSs have been proposed as promising tools for engineering selective antimicrobial platforms.