T6SS-Effector Hunters Uncover PIX: A Novel Delivery/Marker Domain
Gram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raisin...
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Universidad de Sevilla (US) |
| Repositorio: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:dnet:idus________::befc0982a4be90e97753b895b1e95ce6 |
| Acceso en línea: | https://hdl.handle.net/11441/185742 https://doi.org/10.1016/j.tim.2024.04.009 |
| Access Level: | acceso abierto |
| Palabra clave: | T6SS marker Effectors Anti-eukaryotic Anti-microbial Delivery domain MIX FIX RIX PIX |
| Sumario: | Gram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raising novel questions in the field. |
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