A New Classification of the Severity of Psoriasis

The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs w...

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Autores: Salgado Boquete, Laura|||0000-0002-0114-5469, Carrascosa, José Manuel|||0000-0003-4266-0771, Llamas-Velasco, Mar|||0000-0002-1187-1341, Ruíz Villaverde, Ricardo|||0000-0002-0381-6174, De la Cueva, Pablo|||0000-0003-4807-3551, Belinchón, Isabel|||0000-0002-6007-7320
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:256467
Acceso en línea:https://ddd.uab.cat/record/256467
https://dx.doi.org/urn:doi:10.3390/life11070627
Access Level:acceso abierto
Palabra clave:Classification
Cut-offs
Discrimination
Moderate
Psoriasis
Severity
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spelling A New Classification of the Severity of PsoriasisWhat's Moderate Psoriasis?Salgado Boquete, Laura|||0000-0002-0114-5469Carrascosa, José Manuel|||0000-0003-4266-0771Llamas-Velasco, Mar|||0000-0002-1187-1341Ruíz Villaverde, Ricardo|||0000-0002-0381-6174De la Cueva, Pablo|||0000-0003-4807-3551Belinchón, Isabel|||0000-0002-6007-7320ClassificationCut-offsDiscriminationModeratePsoriasisSeverityThe purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe.Universitat Autònoma de Barcelona 22021-01-0120212021-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/256467https://dx.doi.org/urn:doi:10.3390/life11070627reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2564672026-06-06T12:50:31Z
dc.title.none.fl_str_mv A New Classification of the Severity of Psoriasis
What's Moderate Psoriasis?
title A New Classification of the Severity of Psoriasis
spellingShingle A New Classification of the Severity of Psoriasis
Salgado Boquete, Laura|||0000-0002-0114-5469
Classification
Cut-offs
Discrimination
Moderate
Psoriasis
Severity
title_short A New Classification of the Severity of Psoriasis
title_full A New Classification of the Severity of Psoriasis
title_fullStr A New Classification of the Severity of Psoriasis
title_full_unstemmed A New Classification of the Severity of Psoriasis
title_sort A New Classification of the Severity of Psoriasis
dc.creator.none.fl_str_mv Salgado Boquete, Laura|||0000-0002-0114-5469
Carrascosa, José Manuel|||0000-0003-4266-0771
Llamas-Velasco, Mar|||0000-0002-1187-1341
Ruíz Villaverde, Ricardo|||0000-0002-0381-6174
De la Cueva, Pablo|||0000-0003-4807-3551
Belinchón, Isabel|||0000-0002-6007-7320
author Salgado Boquete, Laura|||0000-0002-0114-5469
author_facet Salgado Boquete, Laura|||0000-0002-0114-5469
Carrascosa, José Manuel|||0000-0003-4266-0771
Llamas-Velasco, Mar|||0000-0002-1187-1341
Ruíz Villaverde, Ricardo|||0000-0002-0381-6174
De la Cueva, Pablo|||0000-0003-4807-3551
Belinchón, Isabel|||0000-0002-6007-7320
author_role author
author2 Carrascosa, José Manuel|||0000-0003-4266-0771
Llamas-Velasco, Mar|||0000-0002-1187-1341
Ruíz Villaverde, Ricardo|||0000-0002-0381-6174
De la Cueva, Pablo|||0000-0003-4807-3551
Belinchón, Isabel|||0000-0002-6007-7320
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universitat Autònoma de Barcelona
dc.subject.none.fl_str_mv Classification
Cut-offs
Discrimination
Moderate
Psoriasis
Severity
topic Classification
Cut-offs
Discrimination
Moderate
Psoriasis
Severity
description The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe.
publishDate 2021
dc.date.none.fl_str_mv 2
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/256467
https://dx.doi.org/urn:doi:10.3390/life11070627
url https://ddd.uab.cat/record/256467
https://dx.doi.org/urn:doi:10.3390/life11070627
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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