A New Classification of the Severity of Psoriasis: What's Moderate Psoriasis?
The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs w...
| Authors: | , , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2021 |
| Country: | España |
| Institution: | Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL) |
| Repository: | r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante |
| OAI Identifier: | oai:isabial.fundanetsuite.com:p8162 |
| Online Access: | https://isabial.portalinvestigacion.com/publicaciones8162 https://www.mdpi.com/2075-1729/11/7/627/htm |
| Access Level: | Open access |
| Keyword: | classification cut-offs discrimination moderate psoriasis severity |
| Summary: | The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI = 11 or BSA = 10 or sPGA = 3), while two steps are required for mild ((2 out 3 are met: PASI = 3 or BSA = 5 or sPGA = 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI = 11 or BSA = 10 or sPGA = 3) but has a DLQI = 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe. |
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