A New Classification of the Severity of Psoriasis

The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs w...

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Detalhes bibliográficos
Autores: Salgado Boquete, Laura|||0000-0002-0114-5469, Carrascosa, José Manuel|||0000-0003-4266-0771, Llamas-Velasco, Mar|||0000-0002-1187-1341, Ruíz Villaverde, Ricardo|||0000-0002-0381-6174, De la Cueva, Pablo|||0000-0003-4807-3551, Belinchón, Isabel|||0000-0002-6007-7320
Tipo de documento: artigo
Data de publicação:2021
País:España
Recursos:Universitat Autònoma de Barcelona
Repositório:Dipòsit Digital de Documents de la UAB
Idioma:inglês
OAI Identifier:oai:ddd.uab.cat:256467
Acesso em linha:https://ddd.uab.cat/record/256467
https://dx.doi.org/urn:doi:10.3390/life11070627
Access Level:Acceso aberto
Palavra-chave:Classification
Cut-offs
Discrimination
Moderate
Psoriasis
Severity
Descrição
Resumo:The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe.