Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors

A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.

Detalles Bibliográficos
Autores: Moreno Clavijo, Elena, Carmona Asenjo, Ana Teresa, Moreno Vargas, Antonio José, Molina Sanz, Lidia, Robina Ramírez, Inmaculada
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/97389
Acceso en línea:https://hdl.handle.net/11441/97389
https://doi.org/10.2533/chimia.2011.40
Access Level:acceso abierto
Palabra clave:Fucosidases 
Glycosidas inhibitors 
Iminosugars
Pyrrolidines
Descripción
Sumario:A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.

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