Hydroxytyrosol supplementation improves antioxidant and anti-inflammatory status in individuals with overweight and prediabetes: A randomized, double-blind, placebo-controlled parallel trial

[Background & aim] Hydroxytyrosol (HT), an olive-derived phenolic compound, possesses well-known antioxidant and anti-inflammatory properties. While its benefits in healthy individuals and as part of extra virgin olive oil are well studied, its preventive role as a dietary supplement in at-risk...

Descripción completa

Detalles Bibliográficos
Autores: Moratilla-Rivera, Ignacio, Pérez-Jiménez, Jara, Ramos, Sonia, Portillo, María P., Martín, M. Ángeles, Mateos, Raquel
Tipo de recurso: artículo
Estado:Versión enviada para evaluación y publicación
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/399889
Acceso en línea:http://hdl.handle.net/10261/399889
Access Level:acceso abierto
Palabra clave:Hydroxytyrosol
Prediabetes
Overweight
Aging
Antioxidant
Anti-inflammatory
Descripción
Sumario:[Background & aim] Hydroxytyrosol (HT), an olive-derived phenolic compound, possesses well-known antioxidant and anti-inflammatory properties. While its benefits in healthy individuals and as part of extra virgin olive oil are well studied, its preventive role as a dietary supplement in at-risk populations remains less explored. This study investigates the potential of HT supplementation in preventing aging-related diseases in overweight individuals with prediabetes.