Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections

In the present study, we describe the investigation of Echinostoma friedi excretory/secretory products using a proteomic approach combined with the use of heterologous antibodies. We have identified 18 protein spots corresponding to ten proteins, including cytoskeletal proteins like actin, tropomyos...

Full description

Bibliographic Details
Authors: Bernal, Dolores, Carpena, Inés, Espert, Ana María, de la Rubia Ortí, José Enrique, Esteban, José Guillermo, Toledo, Rafael, Marcilla, Antonio
Format: article
Publication Date:2006
Country:España
Institution:Universidad Católica de Valencia San Vicente Mártir
Repository:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Language:English
OAI Identifier:oai:riucv.ucv.es:20.500.12466/4483
Online Access:http://hdl.handle.net/20.500.12466/4483
Access Level:Open access
Keyword:Echinostoma friedi
Excretory
Secretory extracts
32 Ciencias Médicas
id ES_23bb0bee5c3a99a901edcda44bf6c16d
oai_identifier_str oai:riucv.ucv.es:20.500.12466/4483
network_acronym_str ES
network_name_str España
repository_id_str
spelling Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infectionsBernal, DoloresCarpena, InésEspert, Ana Maríade la Rubia Ortí, José EnriqueEsteban, José GuillermoToledo, RafaelMarcilla, AntonioEchinostoma friediExcretorySecretory extracts32 Ciencias MédicasIn the present study, we describe the investigation of Echinostoma friedi excretory/secretory products using a proteomic approach combined with the use of heterologous antibodies. We have identified 18 protein spots corresponding to ten proteins, including cytoskeletal proteins like actin, tropomyosin, and paramyosin; glycolytic enzymes like enolase, glyceraldehyde 3P dehydrogenase, and aldolase; detoxifying enzymes like GSTs; and stress proteins like heat shock protein (Hsp) 70. Among these proteins, both actin and, to a lesser extent, Hsp70, exhibited differential expression patterns between chronic and acute infections in the Echinostoma–rodent model, suggesting that these proteins may play a role in the survival within the host.20242024-08-0120062006-01-0120062006-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/20.500.12466/4483reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártirinstname:Universidad Católica de Valencia San Vicente MártirInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:riucv.ucv.es:20.500.12466/44832026-06-19T08:32:07Z
dc.title.none.fl_str_mv Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
title Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
spellingShingle Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
Bernal, Dolores
Echinostoma friedi
Excretory
Secretory extracts
32 Ciencias Médicas
title_short Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
title_full Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
title_fullStr Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
title_full_unstemmed Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
title_sort Identification of proteins in excretory/secretory extracts of Echinostoma friedi (Trematoda) from chronic and acute infections
dc.creator.none.fl_str_mv Bernal, Dolores
Carpena, Inés
Espert, Ana María
de la Rubia Ortí, José Enrique
Esteban, José Guillermo
Toledo, Rafael
Marcilla, Antonio
author Bernal, Dolores
author_facet Bernal, Dolores
Carpena, Inés
Espert, Ana María
de la Rubia Ortí, José Enrique
Esteban, José Guillermo
Toledo, Rafael
Marcilla, Antonio
author_role author
author2 Carpena, Inés
Espert, Ana María
de la Rubia Ortí, José Enrique
Esteban, José Guillermo
Toledo, Rafael
Marcilla, Antonio
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Echinostoma friedi
Excretory
Secretory extracts
32 Ciencias Médicas
topic Echinostoma friedi
Excretory
Secretory extracts
32 Ciencias Médicas
description In the present study, we describe the investigation of Echinostoma friedi excretory/secretory products using a proteomic approach combined with the use of heterologous antibodies. We have identified 18 protein spots corresponding to ten proteins, including cytoskeletal proteins like actin, tropomyosin, and paramyosin; glycolytic enzymes like enolase, glyceraldehyde 3P dehydrogenase, and aldolase; detoxifying enzymes like GSTs; and stress proteins like heat shock protein (Hsp) 70. Among these proteins, both actin and, to a lesser extent, Hsp70, exhibited differential expression patterns between chronic and acute infections in the Echinostoma–rodent model, suggesting that these proteins may play a role in the survival within the host.
publishDate 2006
dc.date.none.fl_str_mv 2006
2006-01-01
2006
2006-01-01
2024
2024-08-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12466/4483
url http://hdl.handle.net/20.500.12466/4483
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.source.none.fl_str_mv reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
instname:Universidad Católica de Valencia San Vicente Mártir
instname_str Universidad Católica de Valencia San Vicente Mártir
reponame_str RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
collection RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869404658481496064
score 15,812429

Similar Items