Importance of interaction between the matrix effect and microbial metabolism in the bioavailability of lignans
[Backgroung] Plant-lignans are polyphenols with low bioavailability and bioactivity that are transformed by the intestinal microbiota into enterolignans. Our hypotheses are: (i) the way in which plant-lignans are ingested in the diet affects, in a decisive way, the microbial metabolism of these comp...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2026 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/412974 |
| Acesso em linha: | http://hdl.handle.net/10261/412974 https://api.elsevier.com/content/abstract/scopus_id/105022307858 |
| Access Level: | acceso abierto |
| Palavra-chave: | Bioaccessibility Bioavailability Enterolignans Flaxseed Health Microbiota |
| Resumo: | [Backgroung] Plant-lignans are polyphenols with low bioavailability and bioactivity that are transformed by the intestinal microbiota into enterolignans. Our hypotheses are: (i) the way in which plant-lignans are ingested in the diet affects, in a decisive way, the microbial metabolism of these compounds and (ii) an increase in lignan bioaccessibility will produce an increase in enterolignans produced by the intestinal microbiota, increasing the bioavailability of lignans ingested in the diet. Therefore, our aims were to determine how the matrix effect affects the metabolism of lignans by the intestinal microbiota and how improving the bioaccessibility of lignans ingested in the diet improves their bioavailability. |
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