Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry

Producción Científica

Detalles Bibliográficos
Autores: Ares Sacristán, Ana María, Alcaide, Lucía, Bernal del Nozal, José, Valverde Bastardo, Silvia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/73296
Acceso en línea:https://doi.org/10.1016/j.foodres.2024.114955
https://uvadoc.uva.es/handle/10324/73296
Access Level:acceso abierto
Palabra clave:Bee pollen
Bisphenols
Food analysis
Food Safety
Green analytical chemistry
Method validation
Risk assessment
Sample treatment
UHPLC-MS/MS
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spelling Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometryAres Sacristán, Ana MaríaAlcaide, LucíaBernal del Nozal, JoséValverde Bastardo, SilviaBee pollenBisphenolsFood analysisFood SafetyGreen analytical chemistryMethod validationRisk assessmentSample treatmentUHPLC-MS/MSProducción CientíficaA new analytical method was developed and validated to determine fourteen bisphenols (A, B, C, E, F, M, P, S, Z, AF, AP, BP, FL, PH) in bee pollen using ultra-high-performance liquid chromatography-tandem mass spectrometry. Two different sample treatments were proposed and evaluated: one based on the QuEChERS (quick, easy, cheap, effective, rugged & safe) approach and the other utilizing microextraction with a supramolecular solvent (SUPRAS). In both cases, average analyte recovery ranged between 71 % and 114 %, and the matrix effect was between −45 % and +5 %, although it was not significant when using the QuEChERS-based method (<±20 %). The environmental impact of both sample treatments was assessed using different analytical metrics, with both procedures classified as environmentally friendly, though slightly better results were obtained for SUPRAS. The method was fully validated, showing that the QuEChERS approach had better overall performance, particularly regarding sensitivity and matrix effect. Consequently, the QuEChERS methodology was applied to determine bisphenols in thirty bee pollen samples from different Spanish regions. Residues of three bisphenols (M, P, and S) were detected, although only bisphenol S was quantified in several samples at low concentration levels (<7 μg kg−1), which is below the established specific migration limit (SML; 50 μg kg−1). However, regarding human health, the estimated daily intake, target hazard quotient, and hazard index assessed were higher than acceptable limits, suggesting a potential risk for human consumers.Ministerio de Igualdad-Instituto de la Mujer (n°10-2-ID22)Elsevier2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.1016/j.foodres.2024.114955https://uvadoc.uva.es/handle/10324/73296reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.sciencedirect.com/science/article/pii/S0963996924010251info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:uvadoc.uva.es:10324/732962026-06-13T12:44:47Z
dc.title.none.fl_str_mv Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
title Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
spellingShingle Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
Ares Sacristán, Ana María
Bee pollen
Bisphenols
Food analysis
Food Safety
Green analytical chemistry
Method validation
Risk assessment
Sample treatment
UHPLC-MS/MS
title_short Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
title_full Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
title_fullStr Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
title_full_unstemmed Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
title_sort Development and validation of a green analytical method for determining fourteen bisphenols in bee pollen by ultra-high-performance liquid chromatography-tandem mass spectrometry
dc.creator.none.fl_str_mv Ares Sacristán, Ana María
Alcaide, Lucía
Bernal del Nozal, José
Valverde Bastardo, Silvia
author Ares Sacristán, Ana María
author_facet Ares Sacristán, Ana María
Alcaide, Lucía
Bernal del Nozal, José
Valverde Bastardo, Silvia
author_role author
author2 Alcaide, Lucía
Bernal del Nozal, José
Valverde Bastardo, Silvia
author2_role author
author
author
dc.subject.none.fl_str_mv Bee pollen
Bisphenols
Food analysis
Food Safety
Green analytical chemistry
Method validation
Risk assessment
Sample treatment
UHPLC-MS/MS
topic Bee pollen
Bisphenols
Food analysis
Food Safety
Green analytical chemistry
Method validation
Risk assessment
Sample treatment
UHPLC-MS/MS
description Producción Científica
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1016/j.foodres.2024.114955
https://uvadoc.uva.es/handle/10324/73296
url https://doi.org/10.1016/j.foodres.2024.114955
https://uvadoc.uva.es/handle/10324/73296
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0963996924010251
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812455

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