Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling

In recent years, the use of free-standing carbonnanotube (CNT) ?lms for neural tissue engineering has attractedtremendous attention. CNT ?lms show large surface area and highelectrical conductivity that combined with ?exibility and biocompat-ibility may promote neuron growth and di?erentiation while...

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Detalles Bibliográficos
Autor: Barrejón Araque, Miriam
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad de Castilla-La Mancha
Repositorio:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/40176
Acceso en línea:https://doi.org/10.1021/acsnano.9b02429
https://hdl.handle.net/10578/40176
Access Level:acceso abierto
Palabra clave:Cross-linking
Functionalization degree
Neuronal behavior
Single-walled carbon nanotube
Synaptic activity
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spelling Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal SignalingBarrejón Araque, MiriamCross-linkingFunctionalization degreeNeuronal behaviorSingle-walled carbon nanotubeSynaptic activityIn recent years, the use of free-standing carbonnanotube (CNT) ?lms for neural tissue engineering has attractedtremendous attention. CNT ?lms show large surface area and highelectrical conductivity that combined with ?exibility and biocompat-ibility may promote neuron growth and di?erentiation whilestimulating neural activity. In addition, adhesion, survival, andgrowth of neurons can be modulated through chemical modi?cationof CNTs. Axonal and synaptic signaling can also be positively tunedby these materials. Here we describe the ability of free-standingCNT ?lms to in?uence neuronal activity. We demonstrate that thedegree of cross-linking between the CNTs has a strong impact onthe electrical conductivity of the substrate, which, in turn, regulatesneural circuit outputs.ACS Publications202520252019info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.1021/acsnano.9b02429https://hdl.handle.net/10578/40176reponame:RUIdeRA. Repositorio Institucional de la UCLMinstname:Universidad de Castilla-La ManchaInglésinfo:eu-repo/semantics/openAccessoai:ruidera.uclm.es:10578/401762026-05-27T07:36:41Z
dc.title.none.fl_str_mv Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
title Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
spellingShingle Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
Barrejón Araque, Miriam
Cross-linking
Functionalization degree
Neuronal behavior
Single-walled carbon nanotube
Synaptic activity
title_short Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
title_full Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
title_fullStr Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
title_full_unstemmed Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
title_sort Chemically Cross-Linked Carbon Nanotube Films Engineered to Control Neuronal Signaling
dc.creator.none.fl_str_mv Barrejón Araque, Miriam
author Barrejón Araque, Miriam
author_facet Barrejón Araque, Miriam
author_role author
dc.subject.none.fl_str_mv Cross-linking
Functionalization degree
Neuronal behavior
Single-walled carbon nanotube
Synaptic activity
topic Cross-linking
Functionalization degree
Neuronal behavior
Single-walled carbon nanotube
Synaptic activity
description In recent years, the use of free-standing carbonnanotube (CNT) ?lms for neural tissue engineering has attractedtremendous attention. CNT ?lms show large surface area and highelectrical conductivity that combined with ?exibility and biocompat-ibility may promote neuron growth and di?erentiation whilestimulating neural activity. In addition, adhesion, survival, andgrowth of neurons can be modulated through chemical modi?cationof CNTs. Axonal and synaptic signaling can also be positively tunedby these materials. Here we describe the ability of free-standingCNT ?lms to in?uence neuronal activity. We demonstrate that thedegree of cross-linking between the CNTs has a strong impact onthe electrical conductivity of the substrate, which, in turn, regulatesneural circuit outputs.
publishDate 2019
dc.date.none.fl_str_mv 2019
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://doi.org/10.1021/acsnano.9b02429
https://hdl.handle.net/10578/40176
url https://doi.org/10.1021/acsnano.9b02429
https://hdl.handle.net/10578/40176
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv ACS Publications
publisher.none.fl_str_mv ACS Publications
dc.source.none.fl_str_mv reponame:RUIdeRA. Repositorio Institucional de la UCLM
instname:Universidad de Castilla-La Mancha
instname_str Universidad de Castilla-La Mancha
reponame_str RUIdeRA. Repositorio Institucional de la UCLM
collection RUIdeRA. Repositorio Institucional de la UCLM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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