Sentinel lymph node biopsy in cutaneous melanoma

PURPOSE: To assess the importance of sentinel lymph node biopsy in patients with cutaneous melanoma. METHODS: Ninety consecutive non-randomized patients with stages I and II melanoma who underwent sentinel lymph node biopsy were followed up prospectively for six years. RESULTS: Patients were followe...

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Detalles Bibliográficos
Autores: Oliveira, Andrea Fernandes de [UNIFESP], Santos, Ivan Dunshee de Abranches Oliveira [UNIFESP], Tucunduva, Thaís Cardoso de Mello [UNIFESP], Sanches, Luciana Garbelini [UNIFESP], Oliveira Filho, Renato Santos de [UNIFESP], Enokihara, Mílvia Maria Simões e Silva [UNIFESP], Ferreira, Lydia Masako [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/3964
Acceso en línea:http://dx.doi.org/10.1590/S0102-86502007000500002
http://repositorio.unifesp.br/handle/11600/3964
Access Level:acceso abierto
Palabra clave:Melanoma
Lymph Nodes
Lymphatic Vessels
Diagnosis
Linfonodos
Vasos Linfáticos
Diagnóstico
Descripción
Sumario:PURPOSE: To assess the importance of sentinel lymph node biopsy in patients with cutaneous melanoma. METHODS: Ninety consecutive non-randomized patients with stages I and II melanoma who underwent sentinel lymph node biopsy were followed up prospectively for six years. RESULTS: Patients were followed up for a mean period of 30 months. Their mean age was 53.3 years, ranging from 12 to 83 years. Thirty patients were male (37.5%) and 50, female (62.5%). Sentinel lymph node was positive in 32.5% and negative in 67.5%. It was found that the thicker the tumor, the greater the incidence of positive sentinel lymph nodes. In the group of patients with positive sentinel lymph nodes, recurrence occurred in 43.5%, but in those with negative sentinel lymph nodes, in only 7%, what points out to the association of tumor recurrence and positive sentinel lymph nodes. There were no major postoperative complications. CONCLUSION: Sentinel lymph node biopsy was demonstrated to be a safe method for selecting patients who need therapeutic lymphadenectomy.