The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies - doi: 10.4025/actascibiolsci.v33i1.6876

Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study...

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Detalles Bibliográficos
Autores: Mantovani, Daniel, Cardozo Filho, Lúcio, Santos, Leonilda Correia, Souza, Vera Lúcia Ferreira de, Watanabe, Cecilia Sumie
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Institución:Universidade Estadual de Maringá (UEM)
Repositorio:Acta Scientiarum Biological Sciences
Idioma:portugués
inglés
OAI Identifier:oai:periodicos.uem.br/ojs:article/6876
Acceso en línea:http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6876
Access Level:acceso abierto
Palabra clave:Daidzein
genistein
functional compounds
soybean
quantity
bioquimica
Descripción
Sumario:Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study aimed identifying and quantifying the isoflavones in products sold at different pharmacies. Isoflavones samples were acquired in six different pharmacies specialized in the production of phytotherapic medications. The isoflavones were extracted, quantified and identified in HPLC. None of the samples, from different pharmacies, presented the isoflavones content presented on the label, i.e., 20 mg. In relation to the isoflavones profile, the highest levels found were of daidzein, with up to 66.8 ± 0.09 µg, being the lowest levels the ones of genistein. It is necessary, therefore, the adoption of methods for the standardization and characterization of the raw materials used by different pharmacies. It would assure the isoflavones content, once they are essential for the effects prescribed by the professionals in the medical area.