Development and validation of a method for the analysis of Ochratoxin A in roasted coffee by liquid chromatography/electrospray-mass spectrometry in Tandem (LC/ESI-MS/MS).

A method using LC/ESI-MS/MS for the quantitative analysis of Ochratoxin A in roasted coffee was described. Linearity was demonstrated (r = 0.9175). The limits of detection and quantification were 1.0 and 3.0 ng g-1, respectively. Trueness, repeatability and intermediate precision values were 89.0-10...

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Detalhes bibliográficos
Autores: BANDEIRA, R. D. C. C., UEKANE, T. M., CUNHA, C. P. da, GEAQUINTO, L. R. O., CUNHA, V. S., CAIXEIRO, J. M. R., GODOY, R. L. O., CRUZ, M. H. C. de la.
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2012
País:Brasil
Recursos:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
Repositório:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Idioma:inglês
OAI Identifier:oai:www.alice.cnptia.embrapa.br:doc/931443
Acesso em linha:http://www.alice.cnptia.embrapa.br/alice/handle/doc/931443
Access Level:Acceso aberto
Palavra-chave:Ocratoxina A
Cromatografia líquida
Espectrometria de massa
Café
Descrição
Resumo:A method using LC/ESI-MS/MS for the quantitative analysis of Ochratoxin A in roasted coffee was described. Linearity was demonstrated (r = 0.9175). The limits of detection and quantification were 1.0 and 3.0 ng g-1, respectively. Trueness, repeatability and intermediate precision values were 89.0-108.8%; 2.4-13.7%; 12.5-17.8%, respectively. To the best of our knowledge, this is the first report in which Ochratoxin A in roasted coffee is analysed by LC/ESI-MS/MS, contributing to the field of mycotoxin analysis, and it will be used for future production of Certified Reference Material.