VALIDATION OF AN INSTRUMENT TO ASSESS ADHERENCE TO HIV PRE-EXPOSURE PROPHYLAXIS (PrEP)
Objective: to adapt and validate the Portuguese version of the Questionnaire for Assessment of Adherence to Antiretroviral Treatment (CEAT-HIV) for use with people taking HIV Pre-Exposure Prophylaxis (PrEP) in Brazil, to assess the metric properties, and to describe the levels of adherence to PrEP o...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | Brasil |
| Institución: | Universidade Federal de Uberlândia (UFU) |
| Repositorio: | Hygeia (Uberlândia) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.www.seer.ufu.br:article/71284 |
| Acceso en línea: | https://seer.ufu.br/index.php/hygeia/article/view/71284 |
| Access Level: | acceso abierto |
| Palabra clave: | HIV Profilaxia Pré-Exposição Adesão à medicação Propriedades psicométricas Pre-Exposure Prophylaxis Medication adherence Psychometric properties |
| Sumario: | Objective: to adapt and validate the Portuguese version of the Questionnaire for Assessment of Adherence to Antiretroviral Treatment (CEAT-HIV) for use with people taking HIV Pre-Exposure Prophylaxis (PrEP) in Brazil, to assess the metric properties, and to describe the levels of adherence to PrEP observed in the study sample. Methods: the adaptation consisted of adequation (replacement of some items of the CEAT-HIV to adapt it to check adherence to HIV pre-exposure prophylaxis (CEAT-PrEP), and modification of the response format in some items, analysis by a committee of experts, semantic analysis, and pre-test. Psychometric validation was performed with 83 individuals. The psychometric properties of the CEAT-PrEP were analyzed by evidences of validity related to relevant external criteria. Reliability and test-retest were analyzed using Cronbach's alpha and the intraclass correlation coefficient (ICC), respectively. Results: after the adaptation process was completed, 83 participants were assessed, aged between 22 and 73, 86.7% men. The instrument's reliability (Cronbach's alpha) was 0.74 (dimensions: compliance with treatment 0.64 and barriers to adherence 0.68). Test-retest (ICC) 0.64 for overall adherence. 61.4% of the sample showed some degree of insufficiency in adherence. The group with higher self-esteem presented fewer barriers to adherence to treatment. Conclusion: the adaptation of the instrument was successful, therefore CEAT-PrEP is recommended for use in research and health services. |
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