Synthesis of 2,3,5,6-tetra-O-benzyl-D-galactofuranose for α-glycosidation
The synthesis of 2,3,5,6-tetra-O-benzyl-D-galactofuranose, a useful compound for α-glycosylation studies, is described. Direct anomeric O-alkylation of galactose was employed for alpha-allylation to yield pure allyl α-D-galactofuranoside, which is a versatile precursor for the synthesis of galactofu...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2006 |
| País: | Argentina |
| Institución: | Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales |
| Repositorio: | Biblioteca Digital (UBA-FCEN) |
| Idioma: | inglés |
| OAI Identifier: | paperaa:paper_14246376_v2005_n12_p234_Gola |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p234_Gola |
| Access Level: | acceso abierto |
| Palabra clave: | α-Galactofuranosyl 1,2-cis-glycosylation Allyl galactofuranoside Galactofuranose |
| Sumario: | The synthesis of 2,3,5,6-tetra-O-benzyl-D-galactofuranose, a useful compound for α-glycosylation studies, is described. Direct anomeric O-alkylation of galactose was employed for alpha-allylation to yield pure allyl α-D-galactofuranoside, which is a versatile precursor for the synthesis of galactofuranose-containing oligosaccharides. Allyl removal of the benzylated galactofuranosyl derivative was performed using palladium (II) chloride as catalyst. ©ARKAT. |
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