Effect of daily consumption of Lactobacillus reuteri CRL 1098 on cholesterol reduction in hypercholesterolemic subjects

The effect of daily consumption of a yogurt containing Lactobacillus reuteri CRL 1098 on the lipid profile of hypercholesterolemic subjects was evaluated by performing a prospective, randomized, double-blind, cross-over placebo Controlled clinical study. Participants consumed daily a yogurt containi...

Descripción completa

Detalles Bibliográficos
Autores: Malpeli, Agustina, Taranto, Maria Pia, Cravero, Ricardo C., Tavella, Marina, Fasano, Maria Victoria, Vicentin, Dimas, Ferrari, Guillermina, Magrini, Graciano, Hebert, Elvira Maria, Font, Graciela Maria, Varea, Ana María, Tavella, Julio Marcelo, González, Horacio F.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/113174
Acceso en línea:http://hdl.handle.net/11336/113174
Access Level:acceso abierto
Palabra clave:LACTOBACILLUS
HIPERCHOLESTEROLAEMIA
PROBIOTICS
FUNCTIONAL FOOD
CARDIOVASCULAR RISK
https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
Descripción
Sumario:The effect of daily consumption of a yogurt containing Lactobacillus reuteri CRL 1098 on the lipid profile of hypercholesterolemic subjects was evaluated by performing a prospective, randomized, double-blind, cross-over placebo Controlled clinical study. Participants consumed daily a yogurt containing L. reuteri CRL 1098 or a placebo for four weeks, separated by a wash-out period. Total cholesterol, triacylglycerol, high-density (HDL) and low-density (LDL) lipoprotein levels were assessed at the beginning and at the end of each period. We found a statistically significant reduction of total (-7.86 g/dl) and LDL (-7.02 g/dl) cholesterol in absolute changes (before-after) as well as a decreasing trend in the group receiving the yogurt containing L. reuteri with respect to the placebo group, without detecting changes in HDL-cholesterol and triacylglycerol levels. Our results suggest that low amounts of yogurt (125 g/day) and low doses of the CRL 1098 strain (106 CFU) are sufficient to reduce total and LDL-cholesterol levels in hypercholesterolemic subjects.

Similares en LA Referencia