Effect of Daily Consumption of Lactobacillus reuteri CRL 1098 on Cholesterol Reduction in Hypercholesterolemic Subjects

The effect of daily consumption of a yogurt containing Lactobacillus reuteri CRL 1098 on the lipid profile of hypercholesterolemic subjects was evaluated by performing a prospective, randomized, double-blind, cross-over placebo controlled clinical study. Participants consumed daily a yogurt containi...

Descripción completa

Detalles Bibliográficos
Autores: Malpeli, Agustina, Taranto, María Pía, Cravero, Ricardo C., Tavella, Marina, Fasano, María Victoria, Vicentin, Dimas, Ferraris, Guillermina, Magrini, Graciano, Hébert, Elvira, Font de Valdez, Graciela, Varea, Ana M., Tavella, Julio M., González, Horacio Federico
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Universidad Nacional de La Plata
Repositorio:SEDICI (UNLP)
Idioma:español
OAI Identifier:oai:sedici.unlp.edu.ar:10915/120532
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/120532
Access Level:acceso abierto
Palabra clave:Ciencias Médicas
Lactobacillus reuteri
Hypercholesterolemia
Cardiovascular risk
Probiotics
Functional foods
Descripción
Sumario:The effect of daily consumption of a yogurt containing Lactobacillus reuteri CRL 1098 on the lipid profile of hypercholesterolemic subjects was evaluated by performing a prospective, randomized, double-blind, cross-over placebo controlled clinical study. Participants consumed daily a yogurt containing L. reuteri CRL 1098 or a placebo for four weeks, separated by a wash-out period. Total cholesterol, triacylglycerol, high-density (HDL) and low-density (LDL) lipoprotein levels were assessed at the beginning and at the end of each period. We found a statistically significant reduction of total (−7.86 g/dl) and LDL (−7.02 g/dl) cholesterol in absolute changes (before-after) as well as a decreasing trend in the group receiving the yogurt containing L. reuteri with respect to the placebo group, without detecting changes in HDL-cholesterol and triacylglycerol levels. Our results suggest that low amounts of yogurt (125 g/day) and low doses of the CRL 1098 strain (106 CFU) are sufficient to reduce total and LDL-cholesterol levels in hypercholesterolemic subjects.

Similares en LA Referencia