Development of a highly efficient oil degumming process using a novel phosphatidylinositol-specific phospholipase C enzyme

Enzymatic degumming using phospholipase C (PLC) enzymes may be used in environmentally friendly processes with improved oil recovery yields. In this work, phosphatidylinositol-specific phospholipase C (PIPLC) candidates obtained from an in silico analysis were evaluated for oil degumming. A PIPLC fr...

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Detalhes bibliográficos
Autores: Cerminati, Sebastián, Eberhardt, Maria Florencia, Elena, Claudia E., Peirú, Salvador, Castelli, Maria Eugenia, Menzella, Hugo Gabriel
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2017
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositório:CONICET Digital (CONICET)
Idioma:inglês
OAI Identifier:oai:ri.conicet.gov.ar:11336/50530
Acesso em linha:http://hdl.handle.net/11336/50530
Access Level:Acceso aberto
Palavra-chave:Enzymatic Degumming
Green Chemistry
Phosphatidylinositol Phospholipase C
Phospholipid Removal
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
Descrição
Resumo:Enzymatic degumming using phospholipase C (PLC) enzymes may be used in environmentally friendly processes with improved oil recovery yields. In this work, phosphatidylinositol-specific phospholipase C (PIPLC) candidates obtained from an in silico analysis were evaluated for oil degumming. A PIPLC from Lysinibacillus sphaericus was shown to efficiently remove phosphatidylinositol from crude oil, and when combined with a second phosphatidylcholine and phosphatidylethanolamine-specific phospholipase C, the three major phospholipids were completely hydrolyzed, providing an extra yield of oil greater than 2.1%, compared to standard methods. A remarkably efficient fed-batch Escherichia coli fermentation process producing ∼14 g/L of the recombinant PIPLC enzyme was developed, which may facilitate the adoption of this cost-effective oil-refining process.