B. cereus phospholipase C engineering for efficient degumming of vegetable oil

Enzymatic phospholipid removal (degumming) is a fast-growing and environmentally friendly process for vegetable oil refining. Type C phospholipases (PLC) are the preferred enzymes since they provide an extra yield in the oil recovery. Bacillus cereus PLC can hydrolyze phosphatidylcholine (PC) but ha...

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Detalles Bibliográficos
Autores: Elena, Claudia Edicht, Cerminati, Sebastián, Ravasi, Pablo, Rasia, Rodolfo Maximiliano, Peirú, Salvador, Menzella, Hugo Gabriel, Castelli, Maria Eugenia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/64885
Acceso en línea:http://hdl.handle.net/11336/64885
Access Level:acceso abierto
Palabra clave:Enzymatic Degumming
Phosphatidylethanolamine Removal
Phospholipase
Site-Directed Mutation
https://purl.org/becyt/ford/4.4
https://purl.org/becyt/ford/4
Descripción
Sumario:Enzymatic phospholipid removal (degumming) is a fast-growing and environmentally friendly process for vegetable oil refining. Type C phospholipases (PLC) are the preferred enzymes since they provide an extra yield in the oil recovery. Bacillus cereus PLC can hydrolyze phosphatidylcholine (PC) but has a limited efficiency at removing phosphatidylethanolamine (PE), which together represent ∼70% of the phospholipids present in crude soybean oil. In the present work, we show that the B. cereus PLC mutant F66Y can remove up to 90% of PE while retaining its efficiency at hydrolyzing PC. Oil treatment with the engineered enzyme provides an extra yield of 1.84% making the B. cereus PLC F66Y mutant an attractive candidate for its industrial use.