Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties

The aim of this work was to study Rhamnus purshiana (Cáscara sagrada) extract spray-drying in order to obtain powders with good rheological properties for direct compression (DC) and stability attributes. The experiments were carried out in a Büchi B-290 Mini Spray Dryer using colloidal silicon diox...

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Autores: Gallo, Loreana Carolina, Llabot, Juan Manuel, Allemandi, Daniel Alberto, Bucala, Veronica, Piña, Juliana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/56195
Acceso en línea:http://hdl.handle.net/11336/56195
Access Level:acceso abierto
Palabra clave:Cáscara Sagrada
Direct Compression
Dry Plant Extract
Factorial Design
Rhamnus Purshiana
Spray-Drying
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
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oai_identifier_str oai:ri.conicet.gov.ar:11336/56195
network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
title Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
spellingShingle Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
Gallo, Loreana Carolina
Cáscara Sagrada
Direct Compression
Dry Plant Extract
Factorial Design
Rhamnus Purshiana
Spray-Drying
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
title_short Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
title_full Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
title_fullStr Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
title_full_unstemmed Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
title_sort Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
dc.creator.none.fl_str_mv Gallo, Loreana Carolina
Llabot, Juan Manuel
Allemandi, Daniel Alberto
Bucala, Veronica
Piña, Juliana
author Gallo, Loreana Carolina
author_facet Gallo, Loreana Carolina
Llabot, Juan Manuel
Allemandi, Daniel Alberto
Bucala, Veronica
Piña, Juliana
author_role author
author2 Llabot, Juan Manuel
Allemandi, Daniel Alberto
Bucala, Veronica
Piña, Juliana
author2_role author
author
author
author
dc.subject.none.fl_str_mv Cáscara Sagrada
Direct Compression
Dry Plant Extract
Factorial Design
Rhamnus Purshiana
Spray-Drying
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
topic Cáscara Sagrada
Direct Compression
Dry Plant Extract
Factorial Design
Rhamnus Purshiana
Spray-Drying
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
description The aim of this work was to study Rhamnus purshiana (Cáscara sagrada) extract spray-drying in order to obtain powders with good rheological properties for direct compression (DC) and stability attributes. The experiments were carried out in a Büchi B-290 Mini Spray Dryer using colloidal silicon dioxide as carrier agent. A 25-1 fractional factorial statistical design was used to find adequate spray-drying operating conditions to produce Cáscara sagrada powders with good flow, good compactability properties, high process yield, low moisture content, low hygroscopicity, and caking tendency. Morphology, size, structural and thermal properties of the particles were also evaluated. The operating variables studied were air inlet temperature, atomization air flow rate, pump feed rate, aspiration capacity, and feed solids concentration. The 25-1 factorial experimental design used was a good strategy to establish spray-drying operating conditions to produce Cáscara sagrada extract powders with good properties for direct compression and high process yields. Colloidal silicon dioxide was an effective drying adjuvant. Its use in relatively high concentrations together with low atomization air flow rates improved powder flowability, increased the product's glass transition temperature, and decreased its moisture content and hygroscopicity.
publishDate 2011
dc.date.none.fl_str_mv 2011-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/56195
Gallo, Loreana Carolina; Llabot, Juan Manuel; Allemandi, Daniel Alberto; Bucala, Veronica; Piña, Juliana; Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties; Elsevier Science Sa; Powder Technology; 208; 1; 3-2011; 205-214
0032-5910
CONICET Digital
CONICET
url http://hdl.handle.net/11336/56195
identifier_str_mv Gallo, Loreana Carolina; Llabot, Juan Manuel; Allemandi, Daniel Alberto; Bucala, Veronica; Piña, Juliana; Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties; Elsevier Science Sa; Powder Technology; 208; 1; 3-2011; 205-214
0032-5910
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.powtec.2010.12.021
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0032591010006522
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Sa
publisher.none.fl_str_mv Elsevier Science Sa
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799195203590946816
spelling Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical propertiesGallo, Loreana CarolinaLlabot, Juan ManuelAllemandi, Daniel AlbertoBucala, VeronicaPiña, JulianaCáscara SagradaDirect CompressionDry Plant ExtractFactorial DesignRhamnus PurshianaSpray-Dryinghttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2The aim of this work was to study Rhamnus purshiana (Cáscara sagrada) extract spray-drying in order to obtain powders with good rheological properties for direct compression (DC) and stability attributes. The experiments were carried out in a Büchi B-290 Mini Spray Dryer using colloidal silicon dioxide as carrier agent. A 25-1 fractional factorial statistical design was used to find adequate spray-drying operating conditions to produce Cáscara sagrada powders with good flow, good compactability properties, high process yield, low moisture content, low hygroscopicity, and caking tendency. Morphology, size, structural and thermal properties of the particles were also evaluated. The operating variables studied were air inlet temperature, atomization air flow rate, pump feed rate, aspiration capacity, and feed solids concentration. The 25-1 factorial experimental design used was a good strategy to establish spray-drying operating conditions to produce Cáscara sagrada extract powders with good properties for direct compression and high process yields. Colloidal silicon dioxide was an effective drying adjuvant. Its use in relatively high concentrations together with low atomization air flow rates improved powder flowability, increased the product's glass transition temperature, and decreased its moisture content and hygroscopicity.Fil: Gallo, Loreana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Llabot, Juan Manuel. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Allemandi, Daniel Alberto. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bucala, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Piña, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaElsevier Science Sa2011-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/56195Gallo, Loreana Carolina; Llabot, Juan Manuel; Allemandi, Daniel Alberto; Bucala, Veronica; Piña, Juliana; Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties; Elsevier Science Sa; Powder Technology; 208; 1; 3-2011; 205-2140032-5910CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.powtec.2010.12.021info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0032591010006522info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:46:04Zoai:ri.conicet.gov.ar:11336/56195instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:46:04.899CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
score 15,812429

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