Multiresistance in Escherichia coli associated with Extended Spectrum Beta-lactamases in urine cultures obtained in patients from a province of the Peruvian Amazon

Background: Beta-lactam antibiotics are the most used in the treatment of urinary infections in Peru. Bacterial resistance is frequently produced by the presence of Extended Spectrum Betalactamases (ESBL) in Enterobacteriaceae. Objective: To determine the multi-resistance in E. coli associated to ex...

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Detalles Bibliográficos
Autores: Tamayo-Contreras, Héctor Luis, Campos-Altamirano, María Soledad Lileana, Baca-Choque, Yessenia Cristhely, Bazán-Tanchiva, Luis, Neyra-Rivera, Carlos David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Repositorio:Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Idioma:español
OAI Identifier:oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/1457
Acceso en línea:https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1457
Access Level:acceso abierto
Palabra clave:Betalactamasas
Escherichia coli
infecciones urinarias
resistencia bacteriana
Bacterial resistance
Betalactamases
urinary infections
Descripción
Sumario:Background: Beta-lactam antibiotics are the most used in the treatment of urinary infections in Peru. Bacterial resistance is frequently produced by the presence of Extended Spectrum Betalactamases (ESBL) in Enterobacteriaceae. Objective: To determine the multi-resistance in E. coli associated to extended spectrum beta-lactamases in urine cultures from adults residing in the province of Tambopata-Madre De Dios. The study: Non-experimental, descriptive study, detection and confirmation of ESBL was performed with the double disc technique using ceftazidime, cefotaxime, cefepime, aztreonam and amoxicillin plus clavulanic acid. Microbial resistance and susceptibility was identified using the diffusion disk technique. Findings: 162 strains of E. coli were isolated. Strains with resistance to the antibiotics ampicillin (71%), trimethoprine sulfamethoxazole (49%), ciprofloxacin acid (37%), nalidixic acid (37%) and aztreonam (31%) were identified. Conclusion: There is antimicrobial resistance mediated by ESBL-producing strains of E. coli.