Post-COVID-19 severe cholangiopathy: report of 6 cases

Coronavirus disease 2019 (COVID-19) is a predominantly respiratory tract infection with the capacity to affect other organs. Liver chemistry abnormalities are a frequent manifestation of COVID-19 but are usually transient. We describe the clinical course and most relevant findings of 6 patients who...

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Detalles Bibliográficos
Autores: Santisteban Arenas, Marco Tulio, Osorio Castrillón, Laura Marcela, Guevara Casallas, Luis Gonzalo, Niño Ramírez, Sebastián Fernando
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Perú
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Idioma:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/1330
Acceso en línea:https://revistagastroperu.com/index.php/rgp/article/view/1330
Access Level:acceso abierto
Palabra clave:Cholangitis
Sclerosing
Coronavirus Infections
Alkaline Phosphatase
Colangitis esclerosante
Infecciones por Coronavirus
Fosfatasa alcalina
Descripción
Sumario:Coronavirus disease 2019 (COVID-19) is a predominantly respiratory tract infection with the capacity to affect other organs. Liver chemistry abnormalities are a frequent manifestation of COVID-19 but are usually transient. We describe the clinical course and most relevant findings of 6 patients who developed a cholangiopathy after severe COVID-19. The mean age of the patients, 4 men and 2 women, was 56 years and the mean time from COVID-19 diagnosis to diagnosis of cholangiopathy was 138 days. The features most important were the increase of alkaline phosphatase and destructuring and beading of the intrahepatic bile duct in magnetic resonance imaging. Cholangiopathy after severe COVID-19 constitutes a novel entity with unique features and po ondary biliary cirrhosis. Further studies are required to understand this disease.