Unidentified dengue serotypes in DENV positive samples and detection of other pathogens responsible for an acute febrile illness outbreak 2016 in Cajamarca, Peru

Objective: To describe the prevalence of dengue virus serotypes, as well as other viral and bacterial pathogens that cause acute febrile illness during an outbreak in Cajamarca in 2016. Results: Dengue virus (DENV) was the most frequent etiologic agent detected in 25.8% of samples (32/124), followed...

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Detalhes bibliográficos
Autores: Del Valle-Mendoza, Juana, Vasquez-Achaya, Fernando, Aguilar-luis, Miguel Angel, Martins-Luna, Johanna, Bazán-Mayra, Jorge, Zavaleta-Gavidia, Victor, Silva-Caso, Wilmer, Carrillo-Ng, Hugo, Tarazona-Castro, Yordi, Aquino-Ortega, Ronald, Del Valle, Luis J.
Formato: artículo
Fecha de publicación:2020
País:Perú
Recursos:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Idioma:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/655508
Acesso em linha:https://doi.org/10.1186/s13104-020-05318-5
http://hdl.handle.net/10757/655508
Access Level:acceso abierto
Palavra-chave:Arbovirus
Chikungunya
Dengue
PCR
Peru
Zika
https://purl.org/pe-repo/ocde/ford#3.00.00
Descrição
Resumo:Objective: To describe the prevalence of dengue virus serotypes, as well as other viral and bacterial pathogens that cause acute febrile illness during an outbreak in Cajamarca in 2016. Results: Dengue virus (DENV) was the most frequent etiologic agent detected in 25.8% of samples (32/124), followed by Rickettsia spp. in 8.1% (10/124), Zika virus in 4.8% (6/124), Chikungunya virus 2.4% (3/124) and Bartonella bacilliformis 1.6% (2/124) cases. No positive cases were detected of Oropouche virus and Leptospira spp. DENV serotypes identification was only achieved in 23% of the total positive for DENV, two samples for DENV-2 and four samples for DENV-4. During the 2016 outbreak in Cajamarca-Peru, it was observed that in a large percentage of positive samples for DENV, the infecting serotype could not be determined by conventional detection assays. This represents a problem for the national surveillance system and for public health due to its epidemiological and clinical implications. Other viral and bacterial pathogens responsible for acute febrile syndrome were less frequently identified.

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