Unidentified dengue serotypes in DENV positive samples and detection of other pathogens responsible for an acute febrile illness outbreak 2016 in Cajamarca, Peru

To describe the prevalence of dengue virus serotypes, as well as other viral and bacterial pathogens that cause acute febrile illness during an outbreak in Cajamarca in 2016. Dengue virus (DENV) was the most frequent etiologic agent detected in 25.8% of samples (32/124), followed by Rickettsia spp....

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Detalles Bibliográficos
Autores: Valle Mendoza, Juana del, Vásquez Achaya, Fernando, Aguilar Luis, Miguel Angel, Martins Luna, Johanna Elizabeth, Bazan Mayra, Jorge, Zabaleta Gavidia, Víctor, Silva Caso, Wilmer, Carrillo Ng, Hugo, Tarazona Castro, Yordi Qesler, Aquino Ortega, Ronald, Valle Mendoza, Luis Javier del|||0000-0001-9916-1741
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/342065
Acceso en línea:https://hdl.handle.net/2117/342065
https://dx.doi.org/10.1186/s13104-020-05318-5
Access Level:acceso abierto
Palabra clave:Virus diseases
Peru
arbovirus
dengue
chikungunya
zika
PCR
Virologia
Virosis
Virus
Descripción
Sumario:To describe the prevalence of dengue virus serotypes, as well as other viral and bacterial pathogens that cause acute febrile illness during an outbreak in Cajamarca in 2016. Dengue virus (DENV) was the most frequent etiologic agent detected in 25.8% of samples (32/124), followed by Rickettsia spp. in 8.1% (10/124), Zika virus in 4.8% (6/124), Chikungunya virus 2.4% (3/124) and Bartonella bacilliformis 1.6% (2/124) cases. No positive cases were detected of Oropouche virus and Leptospira spp. DENV serotypes identification was only achieved in 23% of the total positive for DENV, two samples for DENV-2 and four samples for DENV-4. During the 2016 outbreak in Cajamarca—Peru, it was observed that in a large percentage of positive samples for DENV, the infecting serotype could not be determined by conventional detection assays. This represents a problem for the national surveillance system and for public health due to its epidemiological and clinical implications. Other viral and bacterial pathogens responsible for acute febrile syndrome were less frequently identified.

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