Five years experience in management of complicated infective endocarditis in a national reference center
Objective. To evaluate the epidemiological, clinical, echocardiographic, microbiological characteristics and complications of patients with complicated infective endocarditis (IE) in a Peruvian refence hospital. Material and methods. A retrospective, descriptive study was carried out reviewing the m...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2020 |
| País: | Perú |
| Institución: | Instituto Nacional Cardiovascular |
| Repositorio: | Archivos peruanos de cardiología y cirugía cardiovascular |
| Idioma: | español |
| OAI Identifier: | oai:apcyccv.org.pe:article/77 |
| Acceso en línea: | https://apcyccv.org.pe/index.php/apccc/article/view/77 |
| Access Level: | acceso abierto |
| Palabra clave: | mortalidad complicaciones endocarditis hemocultivo mortality complications blood culture |
| Sumario: | Objective. To evaluate the epidemiological, clinical, echocardiographic, microbiological characteristics and complications of patients with complicated infective endocarditis (IE) in a Peruvian refence hospital. Material and methods. A retrospective, descriptive study was carried out reviewing the medical records of patients diagnosed with IE treated at Instituto Nacional Cardiovascular-INCOR between years 2012 and 2016; collecting clinical, imaging and laboratory variables. Results. 59 cases were included, predominantly males (66.1%) and the median age was 50 years (IQR 37-62). The most frequent comorbidities were congenital heart disease (42.3%) and the presence of a prosthetic valve (23.7%). The most frequent sign found in the physical examination was fever (69.49%) and the most common symptom was dyspnea (52.5%). The proportion of positive blood cultures was 55.9%, and in 51.5% of these the isolated pathogen was Staphylococcus spp. The most affected valve was the aortic (72.8%), the most frequent finding by echocardiography was the presence of vegetations (91.5%). The most common complications were atrioventricular block (28.8%) and heart failure (22%). Overall, in-hospital mortality was 20.3%. Conclusion. IE continues to be a challenging pathology, our clinical-epidemiological results are comparable to those found internationally, which reflect the change in the microbiology and in its epidemiology. However, despite advances in diagnosis and treatment, mortality remains unchanged. |
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