Características clínicas y epidemiológicas de la endocarditis infecciosa en el Hospital Nacional Dos de Mayo, 2014-2019

Introduction. Infective Endocarditis (IE) is a disease caused by the invasion of pathogenic organisms into the cardiac endothelium. Objectives. To determine the clinical and epidemiological characteristics of Infectious Endocarditis in the Hospital Nacional Dos de Mayo, 2014-2019,...

ver descrição completa

Detalhes bibliográficos
Autores: Ferrer Rodríguez, Carolina, Fu Llampasi, Martha, Espíritu, Nora, Parhuana Bando, Alejandra
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Recursos:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/19503
Acesso em linha:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/19503
Access Level:acceso abierto
Palavra-chave:Endocarditis
Epidemiología Descriptiva
Complicaciones
Mortalidad
Epidemiology, Descriptive
Complications
Mortality
Descrição
Resumo:Introduction. Infective Endocarditis (IE) is a disease caused by the invasion of pathogenic organisms into the cardiac endothelium. Objectives. To determine the clinical and epidemiological characteristics of Infectious Endocarditis in the Hospital Nacional Dos de Mayo, 2014-2019, Lima-Perú. Methods. Observational, descriptive and retrospective study. Patients older than 18 years with a diagnosis of IE according to modified Duke criteria, who had a complete blood count, blood culture, and echocardiogram were included. Results. 26 patients were studied; the average age was 46,96 ± 15,6 years, males predominated (57,7%), 15 came from Lima and 50% had completed secondary education as a degree. 57,7% (n = 15) had a negative blood culture, the most frequent symptoms were heart murmur (67,6%), fever (26%) and dyspnea (23,4%), the predominant complication was heart failure (61%). Comorbidities (47,1%) were the main risk factor. The mitral valve (51,7%) was the most compromised. The antibiotic regimen vancomycin + ceftriaxone and vancomycin + gentamicin, both with 19,2%, were the most used. 84,6% had erythrocyte distribution width (RDW) values > 14,4%. Of 10 who died, 9 had RDW > 14,4%. Conclusions. IE mainly affects males over 50 years of age with concomitant comorbidities. Positive echocardiography together with the Duke minor criteria were predominant. Most presented high RDW values that were related to the presence of complications and mortality, which was high.