Factors associated with nonadherence to antiretroviral therapy in people with HIV/AIDS

Objective: To determine the association that social, clinical and therapeutic factors and coexisting diseases have with nonadherence to antiretroviral therapy in people with HIV/AIDS in 2018. Materials and methods: A cross-sectional study conducted with a sample of 117 people with HIV/AIDS on antire...

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Detalles Bibliográficos
Autores: Barrera-Espinoza, Richar William, Gómez-Gonzales, Walter Edgar, Girón-Vargas , Ana, Arana-Escobar, Magaly, Nieva-Villegas , Lilia María, Gamarra-Bustillos, Carlos, Auqui-Canchari, María, Zapana-Tito, María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Universidad de San Martín de Porres
Repositorio:Horizonte médico
Idioma:español
OAI Identifier:oai:horizontemedico.usmp.edu.pe:article/1498
Acceso en línea:https://horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/1498
Access Level:acceso abierto
Palabra clave:Adherencia al tratamiento
Terapia antirretroviral
VIH
Síndrome de inmunodeficiencia adquirida
Treatment adherence and compliance
Antiretroviral therapy
HIV
Acquired immunodeficiency síndrome
Descripción
Sumario:Objective: To determine the association that social, clinical and therapeutic factors and coexisting diseases have with nonadherence to antiretroviral therapy in people with HIV/AIDS in 2018. Materials and methods: A cross-sectional study conducted with a sample of 117 people with HIV/AIDS on antiretroviral therapy at the Hospital Daniel Alcides Carrión. The Questionnaire for the Assessment of Adherence to Antiretroviral Therapy (CEAT-VIH)adapted for use in Peru was administered. The IBM SPSS Statistics V23 and logistic regression were used for the statistical analysis. Results: Seventeen point one zero percent (17.10 %) of the patients did not adhere to the therapy and 82.90 % adhered to their prescribed treatment. The variables most likely to predict nonadherence were sex (OR = 16.175, p value = 0.023) and HIV/AIDSrelated comorbidities (OR = 9.556, p value = 0.003). The initial viral load variable (OR = 0.152, p value = 0.030) acts as a protector because there is a greater probability of treatment adherence. Conclusions: Male sex and HIV/AIDS-related comorbidities are associated with the nonadherence to antiretroviral therapy. The initial viral load variable acts as a protector for treatment adherence.