Maternal-fetal hemorrhage after amniocentesis and cordocentesis
Objective: To compare the frequency and amount of maternal-fetal hemorrhagefollowing amniocentesis and cordocentesis. Design: Case-control study.Institución. Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela. Methods:Pregnant women with singleton pregnancies without fetal anomalies u...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | Perú |
| Institución: | Sociedad Peruana de Obstetricia y Ginecología |
| Repositorio: | Revista Peruana de Ginecología y Obstetricia |
| Idioma: | español inglés |
| OAI Identifier: | oai:ginecologiayobstetricia.pe:article/2450 |
| Acceso en línea: | https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2450 |
| Access Level: | acceso abierto |
| Palabra clave: | Hemorragia materno-fetal Amniocentesis Cordocentesis Complicaciones Hemorrhage maternal-fetal Complications |
| Sumario: | Objective: To compare the frequency and amount of maternal-fetal hemorrhagefollowing amniocentesis and cordocentesis. Design: Case-control study.Institución. Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela. Methods:Pregnant women with singleton pregnancies without fetal anomalies undergoingamniocentesis for fetal karyotyping (16–20 weeks’ gestation) or cordocentesis (20–30 weeks’ pregnancy) in the period January 2017-May 2022. Main study outcomes:General characteristics of the procedure, Kleihauer-Brown-Betke test results, andmaternal serum alpha-fetoprotein concentrations. Results: The study sample was305 patients. Amniocentesis was performed in 165 women and cordocentesis in 140cases. De novo maternal-fetal hemorrhage was observed in 8 patients (4.8%) afteramniocentesis and in 41 patients (29.3%) after cordocentesis, de novo maternalfetalhemorrhage was observed in 8 patients (4.8%). Serum alpha-fetoproteinconcentrations increased in 24 cases (14.5%) after amniocentesis and in 55 cases(39.3%) after cordocentesis (p < 0.05). After cordocentesis, higher mean maternalfetalhemorrhage volume, elevation of individual volume values and significantincreases in severe maternal-fetal hemorrhage (more than 5 mL of fetal erythrocytes)and total fetoplacental blood volume loss were observed (p < 0.05). Conclusion:These results show that both amniocentesis and cordocentesis increase the riskof maternal-fetal hemorrhage. However, ultrasound-guided amniocentesis has alower risk of producing hemorrhage and resulting Rh isoimmunization compared tocordocentesis. |
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