EFECTO DE DIAZINÓN SOBRE EL SISTEMA COLINÉRGICO NO NEURONAL EN LINFOCITOS DE TILAPIA NILÓTICA (OREOCHROMIS NILOTICUS)
Diazinon is an organophosphorus pesticide that exerts toxic effects on the immune system. However, the mechanism of immunotoxicity is not yet clear. It has been proposed that the alteration in the immune response by diazinon could be attributed to the non-neuronal cholinergic system present in the c...
| Autores: | , |
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| Tipo de recurso: | tesis de maestría |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | México |
| Institución: | Universidad Autónoma de Nayarit |
| Repositorio: | Repositorio Institucional Aramara de la UAN |
| Idioma: | español |
| OAI Identifier: | oai:dspace.uan.mx:123456789/1615 |
| Acceso en línea: | http://dspace.uan.mx:8080/jspui/handle/123456789/1615 |
| Access Level: | acceso abierto |
| Palabra clave: | DIAZINÓN SISTEMA COLINÉRGICO NEURONAL LINFOCITOS DE TILAPIA NILÓTICA COLINÉRGICO SYSTEM NILÓTIC TILAPIA LYMPHOCYTES CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA [6] |
| Sumario: | Diazinon is an organophosphorus pesticide that exerts toxic effects on the immune system. However, the mechanism of immunotoxicity is not yet clear. It has been proposed that the alteration in the immune response by diazinon could be attributed to the non-neuronal cholinergic system present in the cells of the immune system, a system that until now has been described only in mammalian models and cell lines. However, fish, being the first group of vertebrates that developed mechanisms of innate and adaptive immunity, represent a potential model for studying the mechanisms of immunoregulation and the potential damage caused by contaminants. The objective of this work was to evaluate in nilotic tilapia (Oreochromis niloticus) the presence of non-neuronal cholinergic system in cells of the immune system; as well as the effect of diazinon on the non-neuronal lymphocyte cholinergic system, as possible target in diazinon immunotoxicity. |
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