CRISPR / Cas: the future of genetic editing

Since the project of the human genome and the subsequent publication of the sequence of more than 20,000 genes that comprise it, the study of the genomes of many organisms and their editing have been a trend since then, being proposed and discovered new tools that allow the editing of DNA. CRISPR/Ca...

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Detalles Bibliográficos
Autores: Mayboca Padilla, Daniel, Flores Ruiz, Daniel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:México
Institución:UNIVERSIDAD DE SONORA
Repositorio:Epistemus
Idioma:español
OAI Identifier:oai:oai.epistemus.unison.mx:article/94
Acceso en línea:https://epistemus.unison.mx/index.php/epistemus/article/view/94
Access Level:acceso abierto
Palabra clave:CRISPR/Cas
Genomic editing tool
Gene therapy
Antiviral treatment
Edición genómica
Terapia génica
Tratamiento antiviral
Descripción
Sumario:Since the project of the human genome and the subsequent publication of the sequence of more than 20,000 genes that comprise it, the study of the genomes of many organisms and their editing have been a trend since then, being proposed and discovered new tools that allow the editing of DNA. CRISPR/Cas system whose natural function is a defense of bacteria against viral infections, ended up being a breakthrough in the field of genomic sciences, allowing genomic editing at a level of precision greater than the techniques that preceded it. The applications of this system that has been emphasized in recent years, are gene therapy and the Development of alternative antiviral treatments. Despite the advances of CRISPR/Cas, it is still required to increase its specificity to eliminate the appearance of mutations outside the target gene.