Cholinesterase as a biomarker to identify cases of pesticide poisoning

The clinical care of the intoxicated, as well as the epidemiological surveillance activities of the population exposed to pesticides, require reference values ​​to be able to make decisions based on science. Cholinesterases are biomarkers discovered in the early twentieth century that currently work...

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Detalhes bibliográficos
Autores: Benitez, Azucena, Ramírez-Vargas, Marco Antonio
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:México
Recursos:UNIVERSIDAD AUTÓNOMA DEL ESTADO DE HIDALGO
Repositório:Mexican Journal of Medical Research
Idioma:inglês
OAI Identifier:oai:repository.uaeh.edu.mx:article/5577
Acesso em linha:https://repository.uaeh.edu.mx/revistas/index.php/MJMR/article/view/5577
Access Level:Acceso aberto
Palavra-chave:cholinesterase
acetylcholinesterase
pesticides
poisoning
colinesterasa
acetilcolinesterasa
plaguicidas
intoxicación
Descrição
Resumo:The clinical care of the intoxicated, as well as the epidemiological surveillance activities of the population exposed to pesticides, require reference values ​​to be able to make decisions based on science. Cholinesterases are biomarkers discovered in the early twentieth century that currently work as auxiliaries in the diagnosis of acute and chronic poisoning. Methodology: In this study we will review 28 investigations that used as a biomarker the cholinesterase in pesticide poisoning, found in search engines PubMed, Dialnet, Redalyc, Crossreff and Google Scholar. Results: 71.42% of the articles reported a decrease in cholinesterase in the population under study and 28.57% report not having detected a decrease in cholinesterase in the study population. Conclusions: We recommend that researchers always consider the delicacy of these enzymes and remember the most important factors that can affect cholinesterase values ​​in addition to pesticides.