DEVELOPMENT OF A PHENOMENOLOGICAL KINETIC MODEL FOR BUTANOL PRODUCTION USING Clostridium beijerinckii

At the present work the construction of an unstructured kinetic model guided by a phenomenological perspective was carried out to reproduce and simulate experiments regarding butanol production by Clostridium beijerinckii considering the ABE metabolic pathway reported for this genre as a biochemical...

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Detalhes bibliográficos
Autores: H.I. Velázquez-Sánchez, M.C. Montes-Horcasitas, R. Aguilar-López
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2014
País:México
Recursos:Centro de Investigación y de Estudios Avanzados del IPN
Repositório:Redalyc-CINVESTAV
OAI Identifier:oai:redalyc.org:62031166009
Acesso em linha:https://www.redalyc.org/articulo.oa?id=62031166009
Access Level:Acceso aberto
Palavra-chave:Ingeniería
butanol
Modeling
biofuels
Clostridium
phenomenological
Descrição
Resumo:At the present work the construction of an unstructured kinetic model guided by a phenomenological perspective was carried out to reproduce and simulate experiments regarding butanol production by Clostridium beijerinckii considering the ABE metabolic pathway reported for this genre as a biochemical basis for it. Fit and parametric sensitivity analyzes were performed to ensure the model could reproduce experimental kinetics at an overall correlation coecient of 0.9882 and determined its high sensitivity thereof to the determination of the specific cell growth and death rates (maxX and kd) butanol production (maxBut) and biomass / substrate yield calculation (YX=S g). Finally, in silico batch analyzes were conducted at 60, 100, 150 and 200 g / L of initial glucose concentration values obtaining final butanol titers of 12.97, 13.95, 14.2 and 14.3 g / L respectively, which are consistent with the reported in the literature for in vitro experiments.