DEVELOPMENT OF A PHENOMENOLOGICAL KINETIC MODEL FOR BUTANOL PRODUCTION USING Clostridium beijerinckii

At the present work the construction of an unstructured kinetic model guided by a phenomenological perspective was carried out to reproduce and simulate experiments regarding butanol production by Clostridium beijerinckii considering the ABE metabolic pathway reported for this genre as a biochemical...

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Bibliographic Details
Authors: H.I. Velázquez-Sánchez, M.C. Montes-Horcasitas, R. Aguilar-López
Format: article
Status:Published version
Publication Date:2014
Country:México
Institution:Centro de Investigación y de Estudios Avanzados del IPN
Repository:Redalyc-CINVESTAV
OAI Identifier:oai:redalyc.org:62031166009
Online Access:https://www.redalyc.org/articulo.oa?id=62031166009
Access Level:Open access
Keyword:Ingeniería
butanol
Modeling
biofuels
Clostridium
phenomenological
Description
Summary:At the present work the construction of an unstructured kinetic model guided by a phenomenological perspective was carried out to reproduce and simulate experiments regarding butanol production by Clostridium beijerinckii considering the ABE metabolic pathway reported for this genre as a biochemical basis for it. Fit and parametric sensitivity analyzes were performed to ensure the model could reproduce experimental kinetics at an overall correlation coecient of 0.9882 and determined its high sensitivity thereof to the determination of the specific cell growth and death rates (maxX and kd) butanol production (maxBut) and biomass / substrate yield calculation (YX=S g). Finally, in silico batch analyzes were conducted at 60, 100, 150 and 200 g / L of initial glucose concentration values obtaining final butanol titers of 12.97, 13.95, 14.2 and 14.3 g / L respectively, which are consistent with the reported in the literature for in vitro experiments.