EffHunter: A tool for prediction of effector protein candidates in fungal proteomic databases

Pathogens are able to deliver small-secreted, cysteine-rich proteins into plant cells to enable infection. The computational prediction of effector proteins remains one of the most challenging areas in the study of plant fungi interactions. At present, there are several bioinformatic programs that c...

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Detalles Bibliográficos
Autores: Karla Gisel Carreón Anguiano, Ignacio Rodrigo Islas Flores, Julio Vega-Arreguin, Luis Alfonso Sáenz Carbonell, Blondy Beatriz Canto Canché
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:México
Institución:Centro de Investigación Científica de Yucatán
Repositorio:Repositorio Institucional CICY
Idioma:inglés
OAI Identifier:oai:cicy.repositorioinstitucional.mx:1003/1820
Acceso en línea:http://cicy.repositorioinstitucional.mx/jspui/handle/1003/1820
Access Level:acceso abierto
Palabra clave:info:eu-repo/classification/Autores/COMPUTATIONAL PREDICTION
info:eu-repo/classification/Autores/HOST-PATHOGEN INTERACTION
info:eu-repo/classification/Autores/EFFECTOR PROTEINS
info:eu-repo/classification/Autores/FUNGAL SECRETOME
info:eu-repo/classification/cti/2
info:eu-repo/classification/cti/24
info:eu-repo/classification/cti/2415
info:eu-repo/classification/cti/241502
Descripción
Sumario:Pathogens are able to deliver small-secreted, cysteine-rich proteins into plant cells to enable infection. The computational prediction of effector proteins remains one of the most challenging areas in the study of plant fungi interactions. At present, there are several bioinformatic programs that can help in the identification of these proteins; however, in most cases, these programs are managed independently. Here, we present EffHunter, an easy and fast bioinformatics tool for the identification of effectors. This predictor was used to identify putative effectors in 88 proteomes using characteristics such as size, cysteine residue content, secretion signal and transmembrane domains.