Visual acuity development after anti-vegf therapy in diabetic macular edema

Introduction: Diabetic macular edema is the most frequent cause of decreased visual acuity in diabetics. The therapy most used in this pathology is antiangiogenic therapy. Objective: Identify visual acuity modification in patients with macular edema due to diabetic retinopathy after antiangiogenic t...

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Detalles Bibliográficos
Autores: Barba Gallardo, Luis Fernando, Carneado Trejo, Regina, Castañeda Ruiz Esparza, Blanca Briseida, Díaz-Rubio, José Luis
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:México
Institución:UNIVERSIDAD AUTÓNOMA DE AGUASCALIENTES
Repositorio:Luxmédica
Idioma:español
OAI Identifier:oai:revistas.uaa.mx:article/4618
Acceso en línea:https://revistas.uaa.mx/index.php/luxmedica/article/view/4618
Access Level:acceso abierto
Palabra clave:Retinopatía diabética
Edema macular
Diabetes Mellitus
Diabetic Retinopathy
Macular Edema
Descripción
Sumario:Introduction: Diabetic macular edema is the most frequent cause of decreased visual acuity in diabetics. The therapy most used in this pathology is antiangiogenic therapy. Objective: Identify visual acuity modification in patients with macular edema due to diabetic retinopathy after antiangiogenic therapy. Material and methods: An observational, retrospective, non-randomized case study was carried out, convenience sampling, in a population of patients with macular edema due to diabetic retinopathy, a total of 304 medical charts were reviewed, by single blind and two different researchers. A total of 189 files where selected, including only those that had all the approvals according to the inclusion parameters during the period from January 2022 to November 2022. Results: 26 men and 19 women, 60 eyes considered (29 right and 31 left) presenting macular edema due to diabetic retinopathy under treatment with antiangiogenic therapy with Aflibercept, it was found that the lower macular thickness is, the better visual acuity (r=0.73), (p<0.001). Visual acuity changes went, on average, from 0.16 baseline to a result of 0.36, indicating that there is in average a 30% improvement in final visual acuity. Conclusion: Intravitreal injection with Aflibercept as a treatment for macular edema due to diabetic retinopathy shows an improvement in visual acuity by reducing macular thickness.   Fecha de recepción: 23/08/2023 Aceptación de originales: 13/09/2023