Encapsulation efficiency of CdSe/ZnS quantum dots by liposomes determined by thermal lens microscopy

"In this study the encapsulation of core shell carboxyl CdSe/ZnS quantum dots (QDs) by phospholipids liposome complexes is presented. It makes the quantum dots water soluble and photo-stable. Fluorescence self-quenching of the QDs inside the liposomes was observed. Therefore, the thermal lens m...

Descripción completa

Detalles Bibliográficos
Autores: Batalla Mayoral, Jessica; 0000-0003-3903-2985, Cabrera, Humberto; 0000-0001-5555-2265, San Martín Martínez, Eduardo; 0000-0002-9568-9140, Korte, Dorota; 0000-0002-5437-4564, Batalla Mayoral, Jessica, Cabrera, Humberto, San Martín Martínez, Eduardo, Korte, Dorota, Calderón, Antonio, Marín, Ernesto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:México
Institución:Benemérita Universidad Autónoma de Puebla
Repositorio:Repositorio Institucional de Acceso Abierto RIAA-BUAP
Idioma:inglés
OAI Identifier:oai:repositorioinstitucional.buap.mx:20.500.12371/17437
Acceso en línea:https://doi.org/10.1364/BOE.6.003898
https://hdl.handle.net/20.500.12371/17437
Access Level:acceso abierto
Descripción
Sumario:"In this study the encapsulation of core shell carboxyl CdSe/ZnS quantum dots (QDs) by phospholipids liposome complexes is presented. It makes the quantum dots water soluble and photo-stable. Fluorescence self-quenching of the QDs inside the liposomes was observed. Therefore, the thermal lens microscopy (TLM) was found to be an useful tool for measuring the encapsulation efficiency of the QDs by the liposomes, for which an optimum value of 36% was determined. The obtained limit of detection (LOD) for determining QDs concentration by TLM was 0.13 nM. Moreover, the encapsulated QDs showed no prominent cytotoxicity toward Breast cancer cells line MDA-MB-231. This study was supported by UV-visible spectroscopy, high resolution transmission electron microscopy (HRTEM) and dynamic light scattering measurements (DLS)".

Similares en LA Referencia