Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos

The effect of resveratrol on the in vitro maturation (IVM) of ovine (Ovis aries) oocytes and the development of handmade cloned embryos was evaluated. The nuclear maturation and reactive oxygen species (ROS) levels in the oocytes, as well as the early development and morphological cloned embryo qual...

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Autores: José Luis Martínez-Ibarra, Eugenia Adriana Espinoza-Mendoza, Raymundo Rangel-Santos, Demetrio Alonso Ambriz-Garcia, María del Carmen Navarro-Maldonado
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:México
Institución:Universidad Autónoma Metropolitana
Repositorio:Redalyc-UAM
OAI Identifier:oai:redalyc.org:42371698002
Acceso en línea:https://www.redalyc.org/articulo.oa?id=42371698002
https://www.redalyc.org/journal/423/42371698002/
https://www.redalyc.org/journal/423/42371698002/html/
https://www.redalyc.org/journal/423/42371698002/42371698002.epub
https://www.redalyc.org/journal/423/42371698002/movil
Access Level:acceso abierto
Palabra clave:Veterinaria
Ovis aries
Resveratrol
Handmade cloning
Embryo development
In vitro maturation
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spelling Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryosJosé Luis Martínez-IbarraEugenia Adriana Espinoza-MendozaRaymundo Rangel-SantosDemetrio Alonso Ambriz-GarciaMaría del Carmen Navarro-MaldonadoVeterinariaOvis ariesResveratrolHandmade cloningEmbryo developmentIn vitro maturationThe effect of resveratrol on the in vitro maturation (IVM) of ovine (Ovis aries) oocytes and the development of handmade cloned embryos was evaluated. The nuclear maturation and reactive oxygen species (ROS) levels in the oocytes, as well as the early development and morphological cloned embryo quality, were evaluated under different resveratrol concentrations (0, 0.5, 2 and 5 µM). After IVM, no significant difference was observed in the maturation rate of oocytes treated with 0.5 µM (81.3 %) and 2 µM (72 %) resveratrol compared to that of the control group (0 µM) (74.2 %), but the rate significantly decreased at 5 µM (56 %) (p < 0.05). When the oocyte ROS levels were determined, no significant differences among the groups were observed (p > 0.05). For cloned embryo development, the embryos obtained from the oocytes treated with 0.5 µM resveratrol showed higher (p < 0.05) compacted morula rates (10.7 %) compared to the embryos obtained from the oocytes treated with 0, 2 and 5 µM (6.2, 0 and 0 %, respectively). Regarding embryo morphological quality, the embryos from the oocytes treated with 0.5 µM resveratrol showed a lower rate of poor quality morulae (4.7 %) in comparison to those treated with 0, 2 and 5 µM (23.8, 23.3 and 33.3 %, respectively) (p < 0.05). In conclusion, resveratrol showed no significant improvement on the IVM or ROS levels in domestic ovine oocytes. However, treatment with 0.5 µM resveratrol during IVM improved embryo quality and promoted morulae compaction of Ovis aries handmade cloned embryos.Universidad Nacional Autónoma de México2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdf0301-5092https://www.redalyc.org/articulo.oa?id=42371698002https://www.redalyc.org/journal/423/42371698002/https://www.redalyc.org/journal/423/42371698002/html/https://www.redalyc.org/journal/423/42371698002/42371698002.epubhttps://www.redalyc.org/journal/423/42371698002/movil10.22201/fmvz.24486760e.2018.4.491Veterinaria México (México) Num.4 Vol.5reponame:Redalyc-UAMinstname:Universidad Autónoma Metropolitanainstacron:UAMenhttp://www.redalyc.org/revista.oa?id=423Veterinaria Méxicoinfo:eu-repo/semantics/openAccessoai:redalyc.org:423716980022025-03-05T19:08:43Z
dc.title.none.fl_str_mv Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
title Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
spellingShingle Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
José Luis Martínez-Ibarra
Veterinaria
Ovis aries
Resveratrol
Handmade cloning
Embryo development
In vitro maturation
title_short Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
title_full Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
title_fullStr Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
title_full_unstemmed Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
title_sort Effect of resveratrol on the in vitro maturation of ovine (Ovis aries) oocytes and the subsequent development of handmade cloned embryos
dc.creator.none.fl_str_mv José Luis Martínez-Ibarra
Eugenia Adriana Espinoza-Mendoza
Raymundo Rangel-Santos
Demetrio Alonso Ambriz-Garcia
María del Carmen Navarro-Maldonado
author José Luis Martínez-Ibarra
author_facet José Luis Martínez-Ibarra
Eugenia Adriana Espinoza-Mendoza
Raymundo Rangel-Santos
Demetrio Alonso Ambriz-Garcia
María del Carmen Navarro-Maldonado
author_role author
author2 Eugenia Adriana Espinoza-Mendoza
Raymundo Rangel-Santos
Demetrio Alonso Ambriz-Garcia
María del Carmen Navarro-Maldonado
author2_role author
author
author
author
dc.subject.none.fl_str_mv Veterinaria
Ovis aries
Resveratrol
Handmade cloning
Embryo development
In vitro maturation
topic Veterinaria
Ovis aries
Resveratrol
Handmade cloning
Embryo development
In vitro maturation
description The effect of resveratrol on the in vitro maturation (IVM) of ovine (Ovis aries) oocytes and the development of handmade cloned embryos was evaluated. The nuclear maturation and reactive oxygen species (ROS) levels in the oocytes, as well as the early development and morphological cloned embryo quality, were evaluated under different resveratrol concentrations (0, 0.5, 2 and 5 µM). After IVM, no significant difference was observed in the maturation rate of oocytes treated with 0.5 µM (81.3 %) and 2 µM (72 %) resveratrol compared to that of the control group (0 µM) (74.2 %), but the rate significantly decreased at 5 µM (56 %) (p < 0.05). When the oocyte ROS levels were determined, no significant differences among the groups were observed (p > 0.05). For cloned embryo development, the embryos obtained from the oocytes treated with 0.5 µM resveratrol showed higher (p < 0.05) compacted morula rates (10.7 %) compared to the embryos obtained from the oocytes treated with 0, 2 and 5 µM (6.2, 0 and 0 %, respectively). Regarding embryo morphological quality, the embryos from the oocytes treated with 0.5 µM resveratrol showed a lower rate of poor quality morulae (4.7 %) in comparison to those treated with 0, 2 and 5 µM (23.8, 23.3 and 33.3 %, respectively) (p < 0.05). In conclusion, resveratrol showed no significant improvement on the IVM or ROS levels in domestic ovine oocytes. However, treatment with 0.5 µM resveratrol during IVM improved embryo quality and promoted morulae compaction of Ovis aries handmade cloned embryos.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 0301-5092
https://www.redalyc.org/articulo.oa?id=42371698002
https://www.redalyc.org/journal/423/42371698002/
https://www.redalyc.org/journal/423/42371698002/html/
https://www.redalyc.org/journal/423/42371698002/42371698002.epub
https://www.redalyc.org/journal/423/42371698002/movil
10.22201/fmvz.24486760e.2018.4.491
identifier_str_mv 0301-5092
10.22201/fmvz.24486760e.2018.4.491
url https://www.redalyc.org/articulo.oa?id=42371698002
https://www.redalyc.org/journal/423/42371698002/
https://www.redalyc.org/journal/423/42371698002/html/
https://www.redalyc.org/journal/423/42371698002/42371698002.epub
https://www.redalyc.org/journal/423/42371698002/movil
dc.language.none.fl_str_mv en
language_invalid_str_mv en
dc.relation.none.fl_str_mv http://www.redalyc.org/revista.oa?id=423
dc.rights.none.fl_str_mv Veterinaria México
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Veterinaria México
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Autónoma de México
publisher.none.fl_str_mv Universidad Nacional Autónoma de México
dc.source.none.fl_str_mv Veterinaria México (México) Num.4 Vol.5
reponame:Redalyc-UAM
instname:Universidad Autónoma Metropolitana
instacron:UAM
instname_str Universidad Autónoma Metropolitana
instacron_str UAM
institution UAM
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collection Redalyc-UAM
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