Improving cervical cancer screening in Mexico: Results from the Morelos HPV Study

Objective. The purpose of this paper is to describe some ofthe results of the Morelos HPV Study. The main objective ofthe Morelos HPV Study is to evaluate the use of humanpapillomavirus (HPV) DNA testing, as compared to thePapanicolaou (Pap) test, for cervical cancer (CC) screening.Material and Meth...

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Detalles Bibliográficos
Autores: Yvonne Flores, Keerti Shah, David Bishai, Attila Lörincz, Mauricio Hernández, Eduardo Lazcano, Jorge Salmerón
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:México
Institución:Instituto Mexicano del Seguro Social
Repositorio:Redalyc-IMSS
OAI Identifier:oai:redalyc.org:10609713
Acceso en línea:https://www.redalyc.org/articulo.oa?id=10609713
Access Level:acceso abierto
Palabra clave:Salud
Pap
screening
HPV testing
cervical cancer
Descripción
Sumario:Objective. The purpose of this paper is to describe some ofthe results of the Morelos HPV Study. The main objective ofthe Morelos HPV Study is to evaluate the use of humanpapillomavirus (HPV) DNA testing, as compared to thePapanicolaou (Pap) test, for cervical cancer (CC) screening.Material and Methods. The Morelos HPV Study is currentlybeing conducted in Mexico, to examine the possibility of usingHPV testing for CC screening. The HPV testing of self-collectedvaginal and clinician-collected cervical specimens was evaluatedas part of this study. The acceptability of the HPV testing ofself-collected specimens was compared to that of the Pap test.A cost-effectiveness analysis (CEA) and cost-benefit analysis(CBA) was also performed. Results. The Morelos HPV Studyresults indicate that HPV testing has a greater sensitivity todetect cervical intraepithelial neoplasia (CIN) 2/3 and CC thanthe Pap test. Our results also indicate an over-all loweracceptability of the Pap test as compared to the self-collected procedure. The results of the CEA and CBA indicate thatscreening women between the ages of 20-80 for CC usingsome type of HPV testing is always more cost-effective thanscreening for CC using the Pap test. Conclusions. Our resultssuggest that self- and clinician-collected HPV testing could beused in CC prevention programs, as an effective complementor substitute for the Pap test. This paper is available too at:http://www.insp.mx/salud/index.html