Risk factors for cervical cancer among HPV positive women in Mexico

Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 con...

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Detalles Bibliográficos
Autores: Yvonne N Flores, David M Bishai, Keerti V Shah, Daron Ferris, Eduardo Lazcano-Ponce, Attila Lörincz, Mauricio Hernández, Jorge Salmerón
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:México
Institución:Instituto Mexicano del Seguro Social
Repositorio:Redalyc-IMSS
OAI Identifier:oai:redalyc.org:10650108
Acceso en línea:https://www.redalyc.org/articulo.oa?id=10650108
Access Level:acceso abierto
Palabra clave:Salud
HPV
Mexico
screening
risk factors
Cervical cancer
Descripción
Sumario:Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 controls who met the study inclusion criteria were selected from the 7 732 women who participated in the Morelos HPV Study from May 1999 to June 2000. Risk factor information was obtained from interviews and from HPV viral load results. Odds ratios and 95 percent confidence intervals were estimated using unconditional multivariate regression.Results. Increasing age, high viral load, a young age at first sexual intercourse, and a low socio-economic status are associatedwith an increased risk of disease among HPV-positive women. Conclusions. These results could have important implications for future screening activities in Mexico andother low resource countries.