Cost-effectiveness of drug therapy prescribed in special situations at hospital

[Abstract] Objective: The Pharmacy and Therapeutics Committee is an advisory body to the medical management of our hospital. Following Royal Decree 86/2015, which regulates the Pharmacy and Therapeutics Committee of the Balearic Islands, this committee prepared a technical report in which it assesse...

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Autores: González-Morcillo, Gonzalo, Calderon Hernanz, Beatriz, Manuel Rodriguez-Camacho, Juan
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/17537
Acceso en línea:https://hdl.handle.net/20.500.13003/17537
Access Level:acceso abierto
Palabra clave:Pharmacy and Therapeutics Committee
Pharmacotherapeutic Guide
Off-label use
Compassionate Use Trials
Assessment Studies
Clinical Audit
Outcome and Process Assessment
Health Care
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spelling Cost-effectiveness of drug therapy prescribed in special situations at hospitalCoste-efectividad de los medicamentos en situaciones especiales en un hospitalGonzález-Morcillo, GonzaloCalderon Hernanz, BeatrizManuel Rodriguez-Camacho, JuanPharmacy and Therapeutics CommitteePharmacotherapeutic GuideOff-label useCompassionate Use TrialsAssessment StudiesClinical AuditOutcome and Process AssessmentHealth Care[Abstract] Objective: The Pharmacy and Therapeutics Committee is an advisory body to the medical management of our hospital. Following Royal Decree 86/2015, which regulates the Pharmacy and Therapeutics Committee of the Balearic Islands, this committee prepared a technical report in which it assessed the possible internal use of off-label drugs, drugs for compassionate use, and drugs not included in the hospital's pharmacotherapeutic guide. The objective was to analyse the clinical response achieved with the use of these drugs and their associated costs. Method: Retrospective study of drugs whose use was requested from the hospital's Pharmacy and Therapeutics Committee hospital between January and December 2018. We analysed whether the requested treatment achieved the objective established by the physician. The cost was calculated based on the duration of the treatment until the objective was achieved or until treatment was discontinued. Results: In total, 70 requests were analysed: 59% achieved the expected therapeutic goal, 34% were considered to be therapeutic failures, and 7% were lost to follow-up. The overall cost of the 70 authorized treatments was (sic)1,140,240. The average cost per request was (sic)16,288. Oncology and Haematology services submitted more than 50% of the requests, and more than 75% of the budget was allocated to these medical services. Conclusions: More than half of the treatments analysed by the Pharmacy and Therapeutics Committee of the hospital achieved their therapeutic goal, although the economic cost of their use was high.[Resum] Objetivo: La Comisión de Farmacia y Terapéutica, como órgano asesor de la Dirección Médica del hospital y bajo las condiciones del Real Decreto 86/2015, por el que se regula la Comisión de Farmacoterapéutica de las Islas Baleares, elabora un informe técnico donde evalúa la posibilidad de empleo interno de medicamentos off-label, uso compasivo y medicamentos no incluidos en la Guía Farmacoterapéutica del hospital. Asimismo, esta comisión realiza un seguimiento prospectivo de cada una de las solicitudes. El objetivo fue analizar la respuesta clínica alcanzada con el empleo de estos medicamentos, así como el coste asociado. Método: Estudio retrospectivo de los medicamentos solicitados a la Comisión de Farmacia y Terapéutica del hospital entre enero y diciembre de 2018. Se analizó si con cada tratamiento solicitado se alcanzó el objetivo propuesto por el clínico. Para el cálculo del coste se consideró la duración del tratamiento hasta alcanzar el objetivo propuesto o hasta su interrupción. Resultados: De un total de 70 solicitudes analizadas, un 59% alcanzaron el objetivo terapéutico esperado, un 34% fueron consideradas como fracaso terapéutico y hubo un 7% de pérdidas de seguimiento. El coste de las 70 peticiones fue de 1.140.240 €. La media de coste por solicitud fue de 16.288 €. Más del 50% de las solicitudes fueron realizadas por los servicios de oncología y hematología y más del 75% del presupuesto fue destinado a estos dos servicios.Editorial Garsi20202020-11-0120202020-11-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.13003/17537reponame:Docusalutinstname:Conselleria de Salut i Consum del Govern de les Illes BalearsInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessoai:docusalut.com:20.500.13003/175372026-06-22T12:44:07Z
dc.title.none.fl_str_mv Cost-effectiveness of drug therapy prescribed in special situations at hospital
Coste-efectividad de los medicamentos en situaciones especiales en un hospital
title Cost-effectiveness of drug therapy prescribed in special situations at hospital
spellingShingle Cost-effectiveness of drug therapy prescribed in special situations at hospital
González-Morcillo, Gonzalo
Pharmacy and Therapeutics Committee
Pharmacotherapeutic Guide
Off-label use
Compassionate Use Trials
Assessment Studies
Clinical Audit
Outcome and Process Assessment
Health Care
title_short Cost-effectiveness of drug therapy prescribed in special situations at hospital
title_full Cost-effectiveness of drug therapy prescribed in special situations at hospital
title_fullStr Cost-effectiveness of drug therapy prescribed in special situations at hospital
title_full_unstemmed Cost-effectiveness of drug therapy prescribed in special situations at hospital
title_sort Cost-effectiveness of drug therapy prescribed in special situations at hospital
dc.creator.none.fl_str_mv González-Morcillo, Gonzalo
Calderon Hernanz, Beatriz
Manuel Rodriguez-Camacho, Juan
author González-Morcillo, Gonzalo
author_facet González-Morcillo, Gonzalo
Calderon Hernanz, Beatriz
Manuel Rodriguez-Camacho, Juan
author_role author
author2 Calderon Hernanz, Beatriz
Manuel Rodriguez-Camacho, Juan
author2_role author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Pharmacy and Therapeutics Committee
Pharmacotherapeutic Guide
Off-label use
Compassionate Use Trials
Assessment Studies
Clinical Audit
Outcome and Process Assessment
Health Care
topic Pharmacy and Therapeutics Committee
Pharmacotherapeutic Guide
Off-label use
Compassionate Use Trials
Assessment Studies
Clinical Audit
Outcome and Process Assessment
Health Care
description [Abstract] Objective: The Pharmacy and Therapeutics Committee is an advisory body to the medical management of our hospital. Following Royal Decree 86/2015, which regulates the Pharmacy and Therapeutics Committee of the Balearic Islands, this committee prepared a technical report in which it assessed the possible internal use of off-label drugs, drugs for compassionate use, and drugs not included in the hospital's pharmacotherapeutic guide. The objective was to analyse the clinical response achieved with the use of these drugs and their associated costs. Method: Retrospective study of drugs whose use was requested from the hospital's Pharmacy and Therapeutics Committee hospital between January and December 2018. We analysed whether the requested treatment achieved the objective established by the physician. The cost was calculated based on the duration of the treatment until the objective was achieved or until treatment was discontinued. Results: In total, 70 requests were analysed: 59% achieved the expected therapeutic goal, 34% were considered to be therapeutic failures, and 7% were lost to follow-up. The overall cost of the 70 authorized treatments was (sic)1,140,240. The average cost per request was (sic)16,288. Oncology and Haematology services submitted more than 50% of the requests, and more than 75% of the budget was allocated to these medical services. Conclusions: More than half of the treatments analysed by the Pharmacy and Therapeutics Committee of the hospital achieved their therapeutic goal, although the economic cost of their use was high.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-11-01
2020
2020-11-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.13003/17537
url https://hdl.handle.net/20.500.13003/17537
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editorial Garsi
publisher.none.fl_str_mv Editorial Garsi
dc.source.none.fl_str_mv reponame:Docusalut
instname:Conselleria de Salut i Consum del Govern de les Illes Balears
instname_str Conselleria de Salut i Consum del Govern de les Illes Balears
reponame_str Docusalut
collection Docusalut
repository.name.fl_str_mv
repository.mail.fl_str_mv
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